Protein Info for GFF2755 in Hydrogenophaga sp. GW460-11-11-14-LB1

Annotation: Excinuclease ABC subunit A

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 100 200 300 400 500 600 700 800 900 1040 TIGR00630: excinuclease ABC subunit A" amino acids 44 to 666 (623 residues), 837.2 bits, see alignment E=1e-255 PF17760: UvrA_inter" amino acids 170 to 284 (115 residues), 116.4 bits, see alignment E=1.8e-37 PF17755: UvrA_DNA-bind" amino acids 342 to 454 (113 residues), 116.9 bits, see alignment E=1.6e-37

Best Hits

KEGG orthology group: K03701, excinuclease ABC subunit A (inferred from 77% identity to aav:Aave_4708)

Predicted SEED Role

"Excinuclease ABC subunit A" in subsystem DNA repair, UvrABC system

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (1040 amino acids)

>GFF2755 Excinuclease ABC subunit A (Hydrogenophaga sp. GW460-11-11-14-LB1)
LNQNLPPDLNLPGSTGAASRETPSVGEPSPRYLGAALRHASAFLSVRGARTHNLKNIDLD
IPKHALVVITGLSGSGKSSLAFDTLYAEGQRRYVESLSAYARQFLQLMDKPDVDLIEGLS
PAIAIEQKATSHNPRSTVGTVTEIHDYLRLLFARAGTPHCPDHHLPLTSQSVAQMVDTVL
ALPEGTRLMILAPVAREKKGEFTELFADMQAQGYVRFRVDGAVLEAEALPALKKTEKHNI
DVVIDRIKVRADGEEEGVNPLRQRLAESFEAALRLADGRAIAVEMDAAEAGAAPREHGFS
ARFACPLCHYTVGELEPRLFSFNSPMGACPTCDGLGHTEFFDPARVVAFPSLSLASGAIK
GWDRRNGYYFAMIESLAAHYRFNAEAPWESLPDAVQQVLLYGSGEDEVKFSYALESGERA
GKKVSKKHPFEGIVRNFERRYRETDSAAVREELARYRAVQACPECAGSRLRREARHVFVG
EGEQKQPIYKISHVTLGEALAYFQKLELHGAKGDIAARVINEIRQRLKFLNDVGLNYLSL
DRSAETLSGGEAQRIRLASQIGSGLTGVMYVLDEPSIGLHQRDNDRLIATLQHLRDLGNT
VLVVEHDEDMIRTADHVIDMGPGAGVHGGRVMAQGTCEQVMATPDSLTGQYLGGTRQIAV
PARRTPWLPVVKKGEAPKAAPTKPRFPPSPAAERRAAREAAHQATLGELQEIRVVNARGH
NLKGASVAFPVGLLTCVTGVSGSGKSTLVNDTLYAAVARTLYRSHDEPAAHDAIEGIEHF
DKVINVDQSPIGRTPRSNPATYTGLFTGIRELMAEMPTARERGYGPGRFSFNVAGGRCEA
CQGDGVVKVEMHFLPDVYVPCEVCHGQRYNRETLDVQYKGRNIAQILDMTVEQSHAFFSA
VPTLHRKLQTLLDVGLSYIQLGQSATTLSGGEAQRVKLALELSKRDTGRTLYILDEPTTG
LHFADIELLLKVLHQLRDAGNTIVVIEHNLDVIKTADWVIDMGPEGGSGGGTVVAQGTPE
TIAAHPDSHTGRYLRRLLTV