Protein Info for PS417_14020 in Pseudomonas simiae WCS417

Annotation: diguanylate phosphodiesterase

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 513 transmembrane" amino acids 12 to 35 (24 residues), see Phobius details amino acids 237 to 256 (20 residues), see Phobius details PF12792: CSS-motif" amino acids 42 to 232 (191 residues), 121.5 bits, see alignment E=3.4e-39 PF00563: EAL" amino acids 265 to 500 (236 residues), 214.7 bits, see alignment E=1.2e-67

Best Hits

KEGG orthology group: None (inferred from 92% identity to pfs:PFLU2994)

Predicted SEED Role

"Rtn protein"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See A0A1N7UI59 at UniProt or InterPro

Protein Sequence (513 amino acids)

>PS417_14020 diguanylate phosphodiesterase (Pseudomonas simiae WCS417)
MPLTINGPRKRASRYLITSLSALLPIALGVIILHWQAERTLQQSSAQTAQEAVRQFDLML
DNTALAAQALLPLAGQPCDSGAQLALREQVTRRPFVRATTLSWQKNIYCSSLFGSNYMSP
VNPDDYVAGQLWLMNGNPVTPDTALLVYRLVDGDKAAFASIDGYHLTNALRLINLYAHLV
LQVGPNWLGTDGKVRDTAMPVFAVANEHLASERYHYSVNAGMPAGEVWRYMQARYPAMFS
LIVFFGVLAGFLAHWLQKRSSAPTQELQRALGANEFIPYFQPVVRGDTREWAGCEVLMRW
QHPKEGLVRPDLFIPLAEHSGLIVPMTRALLRQTAAQLSPHASRFSPGFHIGVNITARHC
QDLALVDDCREFLAAFPVGQVTLVLELTERELIVPTDITRRLFDALHQLGVMIAIDDFGT
GHSSLGYLRNFNVDYLKIDQSFVAMIGADALSLHILDSIIELSGKLDLGIVAEGVETPEQ
SDYLAAQGVDFLQGYLFGKPLPCDEFIQSLVSH