Protein Info for GFF2738 in Hydrogenophaga sp. GW460-11-11-14-LB1

Annotation: Omega-amino acid--pyruvate aminotransferase (EC 2.6.1.18)

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

• PF00202: Aminotran_3
  • amino acids 26 to 442 (417 residues), 292.1 bits, E=2.9e-91

Best Hits

KEGG orthology group: K00822, beta-alanine--pyruvate transaminase [EC: 2.6.1.18] (inferred from 83% identity to vpe:Varpa_5449)

Predicted SEED Role

"Omega-amino acid--pyruvate aminotransferase (EC 2.6.1.18)" in subsystem Pyruvate Alanine Serine Interconversions (EC 2.6.1.18)

MetaCyc Pathways

• superpathway of coenzyme A biosynthesis II (plants) (9/10 steps found)
• β-alanine biosynthesis II (5/6 steps found)
• β-alanine degradation II (2/2 steps found)

KEGG Metabolic Maps

• Alanine and aspartate metabolism
• Propanoate metabolism
• Valine, leucine and isoleucine degradation
• beta-Alanine metabolism

Isozymes

No predicted isozymes

Use Curated BLAST to search for 2.6.1.18

Protein Sequence (446 amino acids)

>GFF2738 Omega-amino acid--pyruvate aminotransferase (EC 2.6.1.18) (Hydrogenophaga sp. GW460-11-11-14-LB1)
MAYNDFRMDNQWLPFTPNRSFQKDPRVFVAAEGMYFTTHDGRQVIDGISSLWCVGAGHNR
KPINEAIKQQLDTLDYSTAFSISNDKAFRAAEMIAELAPGDLNKVLFCNSGSEAADTSMK
VALAYHRARGEGHRNIFIGRERGYHGVGFGGMSVGGIPANRKVYGAALLPRVDHLRFIHD
PVKHAYVHNTEPVWDEDLLLELENRILPLHDPSNVAAVIVEPVAGSAGWYVPPQGYLKRL
REICDKHGILLIFDEVITGFGRLGTAFASDYYGVQPDMLNFAKAVTNGVFPLGGVVCTDR
IYDAMMGAHGSAPDHAIEFFHGYTYSGHPVACAAAIATLDLFREENLFARAGEMGPVLGD
AMHSALKGLPHVIGIRSFGLAAAVELAPQPGMPGKRAFDVFMDCFHRGVLVRNAGDNLVF
APPYIVDRAQIETMVGTLADAIKRLG