Protein Info for GFF2736 in Pseudomonas sp. DMC3

Annotation: Protein FecR

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 316 PF16220: DUF4880" amino acids 14 to 56 (43 residues), 47.8 bits, see alignment 1.1e-16 PF04773: FecR" amino acids 111 to 199 (89 residues), 53 bits, see alignment E=4e-18

Best Hits

KEGG orthology group: None (inferred from 70% identity to psp:PSPPH_2748)

Predicted SEED Role

"heme uptake transmembrane sensor" in subsystem Hemin transport system

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (316 amino acids)

>GFF2736 Protein FecR (Pseudomonas sp. DMC3)
MRVAPSEETREVARAAAQWLALLESGAASDEDHARLQHWRASDSRHENAWQKIQQLRQRF
AGLPPTLAMATLDRPDPARRAALKRALGVAALVPAAWLISRELPLEAWRADLHTSTGERR
KVQLAQDSSLQLNTDSAVNVDLPARQLTMIRGEMTLNVAGDSAFIVNAPYGRMIVNHSDI
SVRLNARDCQVCVLRGSVQLQPLHGPALVLQQGQQVSLQASGAGAVTAFDALMPGWRDGV
LMAQNQPLGDFLRELSRYRSGVLRWDPALESLRITGSFRLDDTDQVLALLAASLPVDVHT
RTRFWVSLVPRAEKTG