Protein Info for GFF2718 in Variovorax sp. SCN45

Annotation: ABC transporter, ATP-binding protein (cluster 3, basic aa/glutamine/opines)

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

• PF00005: ABC_tran
  • amino acids 22 to 170 (149 residues), 137.3 bits, E=8.7e-44

Best Hits

Swiss-Prot: 74% identical to AAPP_RHIL3: General L-amino acid transport ATP-binding protein AapP (aapP) from Rhizobium leguminosarum bv. viciae (strain 3841)

KEGG orthology group: K02028, polar amino acid transport system ATP-binding protein [EC: 3.6.3.21] (inferred from 98% identity to vpe:Varpa_2198)

MetaCyc: 61% identical to glutamate/aspartate ABC transporter ATP binding subunit (Escherichia coli K-12 substr. MG1655)
ABC-13-RXN [EC: 7.4.2.1]; 7.4.2.1 [EC: 7.4.2.1]

Predicted SEED Role

"amino acid ABC transporter ATP-binding protein"

Isozymes

Compare fitness of predicted isozymes for: 3.6.3.21

Use Curated BLAST to search for 3.6.3.21 or 7.4.2.1

Protein Sequence (251 amino acids)

>GFF2718 ABC transporter, ATP-binding protein (cluster 3, basic aa/glutamine/opines) (Variovorax sp. SCN45)
MTTESIIRMEAVNKWYGEFQVLTGIDLSVRQGERIVICGPSGSGKSTLIRCINRLETVQK
GRIVVDGIDLTAGGKNIDAVRAEVGMVFQQFNLFPHLTILENCTLAPKRSRGMTKAQAEE
IAMKYLTRVRIPEQANKYPSQLSGGQQQRVAIARALCMTPKIMLFDEPTSALDPEMVKEV
LDTMIGLAEDGMTMLCVTHEMGFARSVADRVIFMAEGKIVEQAPPEEFFGNPKDERTRQF
LGQILSSHQGH