Protein Info for GFF2708 in Xanthobacter sp. DMC5

Annotation: Iron(3+)-hydroxamate import system permease protein FhuB

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 550 600 650 675 transmembrane" amino acids 12 to 36 (25 residues), see Phobius details amino acids 47 to 68 (22 residues), see Phobius details amino acids 73 to 93 (21 residues), see Phobius details amino acids 102 to 122 (21 residues), see Phobius details amino acids 131 to 150 (20 residues), see Phobius details amino acids 156 to 178 (23 residues), see Phobius details amino acids 200 to 203 (4 residues), see Phobius details amino acids 210 to 229 (20 residues), see Phobius details amino acids 248 to 273 (26 residues), see Phobius details amino acids 287 to 311 (25 residues), see Phobius details amino acids 317 to 335 (19 residues), see Phobius details amino acids 360 to 380 (21 residues), see Phobius details amino acids 402 to 423 (22 residues), see Phobius details amino acids 435 to 456 (22 residues), see Phobius details amino acids 462 to 479 (18 residues), see Phobius details amino acids 491 to 511 (21 residues), see Phobius details amino acids 536 to 557 (22 residues), see Phobius details amino acids 578 to 601 (24 residues), see Phobius details amino acids 618 to 638 (21 residues), see Phobius details amino acids 648 to 667 (20 residues), see Phobius details PF01032: FecCD" amino acids 29 to 336 (308 residues), 199.3 bits, see alignment E=8.1e-63 amino acids 396 to 668 (273 residues), 214.3 bits, see alignment E=2.1e-67

Best Hits

KEGG orthology group: K02015, iron complex transport system permease protein (inferred from 50% identity to mci:Mesci_5936)

Predicted SEED Role

"Ferric hydroxamate ABC transporter (TC 3.A.1.14.3), permease component FhuB" in subsystem Iron acquisition in Vibrio or Siderophore Aerobactin (TC 3.A.1.14.3)

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (675 amino acids)

>GFF2708 Iron(3+)-hydroxamate import system permease protein FhuB (Xanthobacter sp. DMC5)
MTDLSIVQKTPPWWAGAGVAAGAVLLLVAGVLTLSAARLGQNVSPSAFGHVVVAAGRGDM
TAAIFLYADLPRITVALLAGAMLALSGVLFQEVLLNQLAEPTTLGVSAGAQLALALATLY
SPTLLSVGREWVCLAGSTASLCVVLLLGMGRGFSSFTVILAGLIVSLFAGAAEAILDILN
HERLLSVAIWSTGVLTQNGWGPALFLAERLPFLAIAAWVLIRPMALLALDEATARGLGIP
VAASRLLVLAVAAALAACVVSAVGVIGFVGLAAPALARHAGGRRLAVRIWLAPLLGADLL
LAADQCVLALAPWLPSLPTGTLTAVIGAPILLWMMRTRSAPGGTVPSMDAGGPRAARPAA
RVTGLAVAVVVAAFVALHFGRGPAGWTVDTGPMFDALLPWRWSRLMAAGGAGLLLAVAGV
VLQRLTGNPLASPEVLGVAPAAGLGMIAATLLLPALDAGDRFLAAASGATLALILLLAFA
RRAHAEPERMLVLGVTIATAFGALATALVASGDPRLTGLLSWMAGSTTEATPRDALGVLA
VAAVCVAASPLLVRWLLILPLGEETARSLGLPLRGSRLVLLVFAAVATAAATLAIGPFSF
VGLMAPHMARMLGLRSPFPQIVGAALCGALVTLAADWLGRTLAFPYEIPAGLVAAGLGCP
YLLVALARRSGEARP