Protein Info for GFF2695 in Hydrogenophaga sp. GW460-11-11-14-LB1

Annotation: ATP-dependent helicase DinG/Rad3

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 550 600 650 700 750 777 PF06733: DEAD_2" amino acids 254 to 311 (58 residues), 26.4 bits, see alignment 7.4e-10 PF13307: Helicase_C_2" amino acids 599 to 763 (165 residues), 131.6 bits, see alignment E=4.6e-42

Best Hits

Predicted SEED Role

"ATP-dependent helicase DinG/Rad3" in subsystem DNA repair, bacterial DinG and relatives

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (777 amino acids)

>GFF2695 ATP-dependent helicase DinG/Rad3 (Hydrogenophaga sp. GW460-11-11-14-LB1)
MSTPTLEPSSADTGASAAPVAGPLAREAIALAAFDHVVAHAPGYRARPGQREMAAHIAHT
LSGVSLGDGAVASDAALPARGIAVVQAGTGVGKSAAYASTVIPLALAQQKRVIISTATVA
LQEQLIAKDLPALAASLPQPFSFALAKGRGRYVCRLKLDQLSGGDAASADLFESDDGSAS
DTSAAGVAAQAVASAAAAARWQERGVQYTAWADALDDGSWDGDRDRLDTPPDGGLWGPVA
AERHTCTARHCPSYNSCSYYQARARLAQAQVIVVNHDLLLSTLGLHALPAPQDCYLVFDE
AHHLGSVAQGQFTASMDLMRGHWLDKLPRAVDEVATAIDHRPTIDVAAFTKELKSAQTEL
ARLAMQRIGSLPAWLDLTGRSAGRSPARPGGGAFNEAGAPVVDRFEGGVLPAEWLEVVGK
LHANASSLLKVFEALAAQLKANARENPGDAARFAKLYSRLGVLAPRLQSAQETASYWQQV
AGDGQPPLAKWLEAGVSHGLVTLTAHACPLQPGSLLRNHLWNQVRAAVVTSASLTTCGTF
DHFLHESGLAWDGAVAAREVQSPFDHARQGRLVVVQTTADPKDVDGYTREMLALLMADLR
EVERGALVLFTSRAQMRQAQGLLERGEHGALRDRVLVQGEASRTVLLRRHAERVAEGKPS
VLFGLQSFGEGLDLPGELCEWVFITKLPFASPSDPVGQARADWLKSQGRDPFSELVVPAT
GARLLQWTGRALRTEADEAVVVCYDARLLRQSYGRRMLKGLPPYRLQRRVDGVLTEA