Protein Info for PS417_13590 in Pseudomonas simiae WCS417

Annotation: histidine kinase

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 454 signal peptide" amino acids 1 to 28 (28 residues), see Phobius details transmembrane" amino acids 166 to 188 (23 residues), see Phobius details PF08521: 2CSK_N" amino acids 20 to 161 (142 residues), 31.8 bits, see alignment E=3.5e-11 PF00512: HisKA" amino acids 239 to 301 (63 residues), 52.7 bits, see alignment E=8.8e-18 PF02518: HATPase_c" amino acids 350 to 453 (104 residues), 76.6 bits, see alignment E=5.1e-25 PF13581: HATPase_c_2" amino acids 356 to 432 (77 residues), 30.4 bits, see alignment E=8.3e-11

Best Hits

KEGG orthology group: None (inferred from 93% identity to pfs:PFLU3127)

Predicted SEED Role

"Sensory histidine kinase QseC" in subsystem Orphan regulatory proteins

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See A0A1N7UL24 at UniProt or InterPro

Protein Sequence (454 amino acids)

>PS417_13590 histidine kinase (Pseudomonas simiae WCS417)
MTSIRRRTLTLIIGLLLTGLLVISVLNLHDSNHEIAEVYDAQLAQNARLLQGVMSLPLAS
KDQADLYRAFNKALGEAIPKVDGHPYESKIAFQVWSPKGELLVFTASAPSFAVPPAQPGY
SNIDDLNGREWRGFVLKDKDNGLRIWVGERDDVRSDLVQRIVRHTLWPNVLGSLILAAMV
WLAIGWGLKPLADMAATLRARHSGSLEPMQLTPLPTELEPMQAALNRMLAQIQEMLGRER
RFIADAAHEMRTPLAVLRVHAQNLLEAGTEAERRESLAFLITGVDRTSRLVSQLLTMARL
EPSAGQLTLQTIDLATTVRETLIQLTPWLLSKGLELVFNADDAPYRVTTDPGAINIALTN
LVTNAANFSPEHGVITVKLSQDAKRFVLTVDDQGPGIDESQRERLFELFYSRGNPEGAGL
GLTIVHTIAQHLGGRVHLENLASGGLRATLEIPR