Protein Info for GFF2650 in Methylophilus sp. DMC18

Annotation: p-hydroxybenzoic acid efflux pump subunit AaeB

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 550 600 650 723 signal peptide" amino acids 1 to 32 (32 residues), see Phobius details transmembrane" amino acids 47 to 65 (19 residues), see Phobius details amino acids 72 to 89 (18 residues), see Phobius details amino acids 95 to 115 (21 residues), see Phobius details amino acids 121 to 140 (20 residues), see Phobius details amino acids 146 to 167 (22 residues), see Phobius details amino acids 406 to 428 (23 residues), see Phobius details amino acids 434 to 451 (18 residues), see Phobius details amino acids 462 to 481 (20 residues), see Phobius details amino acids 487 to 504 (18 residues), see Phobius details amino acids 511 to 531 (21 residues), see Phobius details amino acids 543 to 563 (21 residues), see Phobius details PF04632: FUSC" amino acids 48 to 714 (667 residues), 463.2 bits, see alignment E=2.7e-142 PF13515: FUSC_2" amino acids 59 to 189 (131 residues), 35 bits, see alignment E=2.2e-12 PF11744: ALMT" amino acids 75 to 215 (141 residues), 21.3 bits, see alignment E=1.7e-08

Best Hits

Predicted SEED Role

No annotation

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (723 amino acids)

>GFF2650 p-hydroxybenzoic acid efflux pump subunit AaeB (Methylophilus sp. DMC18)
MQRRHALRQGWHALAAGIAILGHGGRWLAICAQQAGLDWYRQDFPLIGYLFKYLLASWLA
LWLALKMEMDQPATALLTVVIVMHFRSGMVITKSYYRLIGTGIGILFSLLLVASFAQDRF
PFFIAAALWIGLCTAGSLVYRNFQSYGFVLAGYTLCIVGLPATLTPWHTFQIASTRMSEI
GVGLLSASLVSELVLPQRLWETIQAVVRGKFRDFSLLLGQRDAVGLNQPVLKFMQDLYQL
ESFRASAQFETDDARVHSTTINQLNLQFMAVSTTYIVFERLQQRLQRSGCKHEAEALQEL
MQPLATAVLSKGQPATSAPELTQLQQAVAAYQQAFTTAFQRRRQALSALPEAQLLTFESG
AALLQRLAAELAAYLDTYVLLVANPRKRQVASREFAAAQLQMHIDWLPVAIAATRGALTL
LVLAVLWMTIDWPSGILAMTLGVITSTLFAGSPTPMATLRQFTLGVVLGIVLVYLSNVFW
LTAAHDYVMLCIVIAPAILLTAWLSARPATALVGAGLGIAYFLMVGFNQALGDLPVKYFN
DSIALMIALAVAAILFSLTDYAASPWARRRLLAQLRGLVVEACLNTTMTAAAFEMRARDL
IQRSGDLHRPQAADSVHVAEALCAALEMGHAVLALRTAAVALPAQPQRLVQHTLLLVAHD
YKQPSRKHQQQVLQWLDHFLVWLQGGEYAQSLSPTQVQKLVTQLHFVRLVIDTEMPALSP
RSL