Protein Info for GFF2649 in Hydrogenophaga sp. GW460-11-11-14-LB1

Annotation: Benzoate transport protein

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 394 signal peptide" amino acids 1 to 37 (37 residues), see Phobius details transmembrane" amino acids 47 to 65 (19 residues), see Phobius details amino acids 72 to 91 (20 residues), see Phobius details amino acids 97 to 116 (20 residues), see Phobius details amino acids 123 to 140 (18 residues), see Phobius details amino acids 146 to 164 (19 residues), see Phobius details amino acids 171 to 189 (19 residues), see Phobius details amino acids 206 to 228 (23 residues), see Phobius details amino acids 249 to 273 (25 residues), see Phobius details amino acids 291 to 316 (26 residues), see Phobius details amino acids 322 to 342 (21 residues), see Phobius details amino acids 354 to 384 (31 residues), see Phobius details PF03594: BenE" amino acids 6 to 382 (377 residues), 449.5 bits, see alignment E=4.6e-139 TIGR00843: benzoate transporter" amino acids 11 to 384 (374 residues), 399.7 bits, see alignment E=6.6e-124

Best Hits

Swiss-Prot: 51% identical to YDCO_ECOLI: Inner membrane protein YdcO (ydcO) from Escherichia coli (strain K12)

KEGG orthology group: K05782, benzoate membrane transport protein (inferred from 76% identity to aav:Aave_4540)

Predicted SEED Role

"Benzoate transport protein" in subsystem Benzoate degradation

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (394 amino acids)

>GFF2649 Benzoate transport protein (Hydrogenophaga sp. GW460-11-11-14-LB1)
MSFFRDVNLSAATAGFVAVLVGFTSSVAIVFQAAQAFGATPAQITSWMWALGLGMGLCSA
IPSLVLRQPVMVAWSTPGAAVLATAGLAGGFTMADAVGAFLISAALIVLVGATGWFERVM
NRIPMAIASALLAGVLARFGLQAFAAAQTALPLVVLMLLAYLLGRRLLPRYAVPLTLAVA
IAYVVARGQFNGGAVSFELAMPVFTLPTFSLAAFTSLALPLFVVTMASQNLPGVAAIRAA
GYDMPISRIITLTGVVTLVLAPFGAFALNLSAITAAICMGPEAHADPKKRYTAAVVCGGI
YVLIGLFGAAITGLLIAFPRELVMAIAGIALLGSIGGGLHAALKDDAHREAALITFLVTL
SGVVIGGIGSAFWGVVAGAIALLVQQYGIHSKKP