Protein Info for GFF2645 in Methylophilus sp. DMC18

Annotation: hypothetical protein

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 190 signal peptide" amino acids 1 to 23 (23 residues), see Phobius details transmembrane" amino acids 33 to 57 (25 residues), see Phobius details amino acids 64 to 85 (22 residues), see Phobius details amino acids 91 to 109 (19 residues), see Phobius details amino acids 115 to 134 (20 residues), see Phobius details amino acids 146 to 165 (20 residues), see Phobius details amino acids 172 to 189 (18 residues), see Phobius details PF04955: HupE_UreJ" amino acids 13 to 187 (175 residues), 138.8 bits, see alignment E=7.4e-45

Best Hits

Swiss-Prot: 34% identical to HUPE_RHILV: Protein HupE (hupE) from Rhizobium leguminosarum bv. viciae

KEGG orthology group: K03192, urease accessory protein (inferred from 46% identity to met:M446_3803)

Predicted SEED Role

No annotation

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (190 amino acids)

>GFF2645 hypothetical protein (Methylophilus sp. DMC18)
MRSDTKYLVTMFLMMWAGSTYAHPGHFDDMMGFFAGFSHPFSGVDHLLSMFAIGLLAGQR
GGKAIMLAPVVCLSAMALACTAAISGLVISFSEMGILLTLVVSGVLLACRVKLSLPLLLP
LVGMFSVFHGYAHGLEMPFNAKGFEYGVGLVAGSSLLLLAGMLTSLKGREKIVAYLGAAT
AVVGLSLLVV