Protein Info for PS417_13455 in Pseudomonas simiae WCS417

Annotation: alkaline proteinase inhibitor

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 122 signal peptide" amino acids 1 to 28 (28 residues), see Phobius details PF02974: Inh" amino acids 31 to 120 (90 residues), 65.6 bits, see alignment E=1.8e-22

Best Hits

KEGG orthology group: None (inferred from 91% identity to pfs:PFLU3145)

Predicted SEED Role

"Alkaline proteinase inhibitor precursor" in subsystem Protein secretion by ABC-type exporters

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See A0A1N7TZE1 at UniProt or InterPro

Protein Sequence (122 amino acids)

>PS417_13455 alkaline proteinase inhibitor (Pseudomonas simiae WCS417)
MQRFFKMITGVLQVMFVSAGAHAMASSLVLPTTAQLAGHWQLHQHDQVCALDLLEQANAL
AGDVACVAQWLGDKPLTWSPTPDGIWLMNAEGSGITHLNRQKEGEYTGRTPTGLEVVLQR
AP