Protein Info for GFF2638 in Variovorax sp. SCN45

Annotation: Putative 2-component regulator

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 374 PF20030: bpMoxR" amino acids 12 to 206 (195 residues), 288.8 bits, see alignment E=3.2e-90 PF07728: AAA_5" amino acids 43 to 170 (128 residues), 83.4 bits, see alignment E=3.1e-27 PF00004: AAA" amino acids 44 to 116 (73 residues), 22.2 bits, see alignment E=3.3e-08 PF17868: AAA_lid_8" amino acids 232 to 285 (54 residues), 33.3 bits, see alignment 7.4e-12

Best Hits

KEGG orthology group: K03924, MoxR-like ATPase [EC: 3.6.3.-] (inferred from 73% identity to pfs:PFLU3481)

Predicted SEED Role

"Putative 2-component regulator"

Isozymes

Compare fitness of predicted isozymes for: 3.6.3.-

Use Curated BLAST to search for 3.6.3.-

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (374 amino acids)

>GFF2638 Putative 2-component regulator (Variovorax sp. SCN45)
MTSNSLQTSAEHVRQAIRAATTGLIGREQLAELIVLSAVAQEHLLVVGPPGTAKSAVVRR
VAQSLGGRYFEYLLGRFTEPSELFGPVDLNKLRAGTVETDVSGMLPEADVAFLDEVFLGS
TAILNTLLGVLNERRFRRGHTQLHCPLRVCVGAANALPDDEGLAAFGDRFLLHVFIEPLP
DHQLEAMLSGGWQSDHAPVATGGALADLDVLCRQLRQVDLGGVQPALANAIRKLRQAGVQ
LSDRRIVKSQRLLAAAAVLAGRLETTEADLWPLLYVLPTQEAQQSARDVLRDVFANATHP
HLLSAVEEATLQPLSRAVRLAESARACLAAEPASARTQAESVLREIDANFSSELLPESLT
ALRTQLVDRLGAPA