Protein Info for PS417_13405 in Pseudomonas simiae WCS417

Annotation: helicase UvrD

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 550 600 650 700 750 815 PF00580: UvrD-helicase" amino acids 131 to 295 (165 residues), 38.7 bits, see alignment E=1.4e-13 amino acids 527 to 602 (76 residues), 44.5 bits, see alignment E=2.4e-15

Best Hits

KEGG orthology group: None (inferred from 93% identity to pfs:PFLU3155)

Predicted SEED Role

"UvrD/REP helicase family protein"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See A0A1N7TZD4 at UniProt or InterPro

Protein Sequence (815 amino acids)

>PS417_13405 helicase UvrD (Pseudomonas simiae WCS417)
MSQQKPDLPPELRPLAEMPLFKRLAARLFGHGLTRLRAQHRFSWLHGQADGFRSGHEAGV
EYGYREGKAEGIEEGRQVLLIRDFRPDEHRAPGVDDSLFDDWRLPLTAELKKRMKADVAR
LLPAHAQPSAAQWKMIFSETPSTSVIAGAGAGKSTSLVLRILLLTHYLGFELSSMTVVTF
TRESRKDFINKLMEILNLWGQPLGVKEAQAVVRTFHSRILPMVRSLPGFERLQAFENLNS
GFEDADSNPFDLRINEAQRQQMNACYHRLHREHPRFRELIAPLARHGLQLKALERDHPDV
QKRVAVTELAAKRDEELCDVIEDLWFRAGAWPIKGIEPNRQTIEINGAQFHCHGYIPELD
AWVVLGFDSRENPQTSRPHSKLSVRAEWAVKRTLFQAFCHKPLIWLDSYESSRRLLSSVA
GDAMAGPGFDYKVKGELASAPLLDSFVAAAGFIENLGLDVPTAVGQMSFAKDDPDRFFFE
ALSIFWKALEDHLLDQSPPIMTYNRMFSLFGENTPENLKLLSDPLLRPLSHLMIDEFQDV
SPQIVSWIRASLREIRSRGPAIHIGRGAQRSSLLCVGDDWQSIYGWRGSSPKYFMAFDKE
FPSPSTTRVMLGENYRSHQHIIDAAEHIVRAAPAIPGKKAKASGAPQALVPVKVLERDDA
ALGRQLSEHYQKGDSILMLYRKSSDKSLIEEHISSVVNVDSSLPPQARRLKQLTYHSAKG
LQADAVFMLGDCQHVTSSPYKNQVYRMAGLGNAGDSEPYDNAQKDEVLRLAYVGITRAVS
HCYWYVEKPEGQAVNVPKASERVDGKKAFFDDQRN