Protein Info for GFF2626 in Variovorax sp. SCN45

Annotation: major facilitator superfamily MFS_1

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 397 transmembrane" amino acids 12 to 32 (21 residues), see Phobius details amino acids 44 to 68 (25 residues), see Phobius details amino acids 80 to 97 (18 residues), see Phobius details amino acids 103 to 125 (23 residues), see Phobius details amino acids 140 to 159 (20 residues), see Phobius details amino acids 166 to 185 (20 residues), see Phobius details amino acids 213 to 234 (22 residues), see Phobius details amino acids 246 to 264 (19 residues), see Phobius details amino acids 276 to 300 (25 residues), see Phobius details amino acids 306 to 325 (20 residues), see Phobius details amino acids 337 to 359 (23 residues), see Phobius details amino acids 366 to 386 (21 residues), see Phobius details PF07690: MFS_1" amino acids 22 to 290 (269 residues), 65 bits, see alignment E=9.2e-22 amino acids 274 to 390 (117 residues), 43.4 bits, see alignment E=3.3e-15 PF12832: MFS_1_like" amino acids 24 to 369 (346 residues), 227 bits, see alignment E=6.1e-71 PF03825: Nuc_H_symport" amino acids 29 to 375 (347 residues), 51.8 bits, see alignment E=1e-17

Best Hits

KEGG orthology group: K05820, MFS transporter, PPP family, 3-phenylpropionic acid transporter (inferred from 92% identity to vpe:Varpa_2267)

Predicted SEED Role

"major facilitator superfamily MFS_1"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (397 amino acids)

>GFF2626 major facilitator superfamily MFS_1 (Variovorax sp. SCN45)
VSAPASVAAGRGHLLAFAGLSASYFAHIGFFNPYLPLWLKDLGLPIFTISLLASVQSITR
VFAPYAWGALSDHTGQRVKLLRFSAAVALASSFGLWWHGGAWWLALVLLVMFTHTSSMMS
LTEAAMAQLVAGDWGRYGRIRLCGSAGFLLTVFVAGEWFERFGMKHFPAWAAGTLAIVLI
ATMKLPDLREPPAAHDAVKAPIGPVLRNPAVRWFFAALFFQVMSHFSVYAFFSLYLDSIG
YSKSTIGLLWALSVVAEIVWFFLQGRLIGLLPMPRWMLVCGIAAVARLGLTAGLGGFVVA
LIVAQWLHALSFAAHHTTCIAVVSRRFPGQLRGRGQALFTVIGYGFGGVLGVLLGGAVAQ
AFGYRTMFAAAAALAVLGSLCAWRVMKLERLERAGRP