Protein Info for GFF2610 in Variovorax sp. SCN45
Annotation: Fructose ABC transporter, permease component FrcC
These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.
Protein Families and Features
Best Hits
KEGG orthology group: K10553, fructose transport system permease protein (inferred from 96% identity to vap:Vapar_3353)Predicted SEED Role
"Fructose ABC transporter, permease component FrcC" in subsystem Fructose utilization
Sequence Analysis Tools
PaperBLAST (search for papers about homologs of this protein)
Search CDD (the Conserved Domains Database, which includes COG and superfam)
Compare to protein structures
Predict protein localization: PSORTb (Gram-negative bacteria)
Predict transmembrane helices and signal peptides: Phobius
Check the current SEED with FIGfam search
Find homologs in fast.genomics or the ENIGMA genome browser
Find the best match in UniProt
Protein Sequence (319 amino acids)
>GFF2610 Fructose ABC transporter, permease component FrcC (Variovorax sp. SCN45) MAKSPTHHIPWGALGPWLALLGACIFFATQSDRFLTGGNLSLILQQVMVVGVIAIGQTLI ILTAGIDLSCGMVMALGGIIMSKFATELGLPAPVAILCGIGVTTLFGLLNGLLVTRIKLP PFIVTLGTLNIAFAITQLYSSSQTITDLPGGLTGLGTTFSIGNAEVAWGAVLMLVLYGLA WFVLRETAAGRHIYAVGNNAEATRLVGIPTQRVLLGVYVAAGVLYGIASLLSVARTGVGD PNAGQTENLDAITAVVLGGTSLFGGRGIVLGSLIGVLIVGVFRNGLTLMGVSSIYQVLVT GVLVILAVTADQLSRRGAR