Protein Info for GFF257 in Hydrogenophaga sp. GW460-11-11-14-LB1

Annotation: Sulfur oxidation molybdopterin C protein

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

• TIGR04555: sulfite dehydrogenase
  • amino acids 32 to 444 (413 residues), 605.8 bits, E=1.9e-186
• PF00174: Oxidored_molyb
  • amino acids 138 to 294 (157 residues), 163.2 bits, E=4.3e-52
• PF03404: Mo-co_dimer
  • amino acids 322 to 431 (110 residues), 60.8 bits, E=1.6e-20

Best Hits

KEGG orthology group: K00360, nitrate reductase (NADH) [EC: 1.7.1.1] K00387, sulfite oxidase [EC: 1.8.3.1] (inferred from 76% identity to har:HEAR1188)

Predicted SEED Role

"Sulfur oxidation molybdopterin C protein" in subsystem Sulfur oxidation

MetaCyc Pathways

• sulfite oxidation IV (sulfite oxidase) (1/1 steps found)
• nitrate reduction II (assimilatory) (1/2 steps found)
• sulfide oxidation IV (mitochondria) (3/5 steps found)
• superpathway of L-methionine salvage and degradation (8/16 steps found)

KEGG Metabolic Maps

• Nitrogen metabolism
• Sulfur metabolism

Isozymes

No predicted isozymes

Use Curated BLAST to search for 1.7.1.1 or 1.8.3.1

Protein Sequence (447 amino acids)

>GFF257 Sulfur oxidation molybdopterin C protein (Hydrogenophaga sp. GW460-11-11-14-LB1)
VSKDLSDVIGRVLPAPENHLSTEKLEQARKARRSFMGKALAMGAGAVTSAAASTRTLAAE
GEEAILKLPAHSTGLGQPVATLGYGLPSKWEGNLQRRQSPGLTRVPQASVSFTPLQGLFG
IITPSGLHFERHHQGWWDIDPSQHRLMVNGLVKRERVFTMDDLMRLPSVSRIHFIECGAN
SAPEWGNVALPSVQYTHGMVSCSEFTGVLLSTLLEMCGYDKKNGKYVLAEGADGSSMTRT
IDIDRAMDDCLVAWAMNGEMLRPENGYPLRLVVPGIQGVSWVKYLRRLEVGDQKWATKDE
AVHYIDHMPDGTHRQYTGIQECKSVITTPSGSQTLLDKGYYNVTGLAWSGRGAIKRVDVS
TDGGRNWRTARLEGPLLPKALTRFNIDWVWDGKPAVLQSRAIDSTGYVQPKINQLRAVRG
TRSIYHQNAIQSWRVAENGEVSNVQVF