Protein Info for GFF2566 in Hydrogenophaga sp. GW460-11-11-14-LB1

Annotation: Indolepyruvate ferredoxin oxidoreductase, alpha and beta subunits

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 100 200 300 400 500 600 700 800 900 1000 1100 1199 PF02775: TPP_enzyme_C" amino acids 488 to 592 (105 residues), 21.9 bits, see alignment E=1.9e-08 PF01558: POR" amino acids 765 to 952 (188 residues), 66.2 bits, see alignment E=6.4e-22 PF20169: DUF6537" amino acids 984 to 1180 (197 residues), 243.8 bits, see alignment E=2.6e-76

Best Hits

Predicted SEED Role

"Indolepyruvate ferredoxin oxidoreductase, alpha and beta subunits" in subsystem Aromatic amino acid interconversions with aryl acids

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (1199 amino acids)

>GFF2566 Indolepyruvate ferredoxin oxidoreductase, alpha and beta subunits (Hydrogenophaga sp. GW460-11-11-14-LB1)
MNAPLPDHIRRALETVTLDDKYALDHGRAFMSGVQALVKLPMLQRQRDALVGKNTAGFIS
GYRGSPLGGYDQALQKAAPYLKAQNIVFQPGVNEELAATALWGTQQLGFAPPGSNRFDGV
FGIWYGKGPGVDRCSDVFKHANMAGTTHWGGVIAVAGDDHVAKSSTAAHQSDHIFKACGL
PVFFPTSVQDILDLGLHALAMSRFSGVWAGMKTIQEIVESSSTAEIDPGRVNIVIPEFEM
PPGGLHIRWPDHALDQEARLFDYKWYAALAYVRANKLNHNVIAGPNDRFGLIASGKAYND
TRQALLDLGLDDGTCRRIGLRLHKVSVVWPLEAQTTREFATGLREILVVEEKRQVIEYQL
KEELYNWRPDVRPNVLGKFDEVEGDFSGGEWSMPNPSAHTLLRANADLSPAIIARAVAKR
LKKIGGVPADVMARIDTHLAVLTAQEQSMQTLLTQGVAGAERQPWFCSGCPHNTSTRVPE
GSRAMAGIGCHFMTIWMDRATVGFTQMGGEGVPWIGQQPFSHDQHMFANLGDGTYFHSGL
LAVRQSIAAGVNITYKILYNDAVAMTGGQQVGERPEGHSVVQIAQSMRAEGAVKIIIVTD
EPEKYDSVKGLPEGIAIQHRDTLDAVQREFREIKGTTVIIYDQTCATEKRRRRKRGTLVD
PDKRVVINELVCEGCGDCGVQSNCLSVEPLETELGRKRTINQSTCNKDYSCVKGFCPSFV
TVEGGQLRKKEKGSAKPEWTGGALPLPVLPTLDSEAWGVIVAGVGGTGVITIGQLLGVAA
HLEGKGIVTQDAAGLAQKGGATWSHVLIGARQDDIRTTRVSAASADLILGCDPIVSAHKE
TWARLRAGRTHVALNVNATPTAAFVKNPDWQNPAQACVDALVSSLGTEAVGAFDAETAAT
RLMGDSLYTNPMMLGYAWQKGWLPLELASLMRAIELNAVQIDKNKAAFEWGRRAAHDPQA
VAALWQKAGAGEQVIQFKKRDSLDTLVARRAEFLTGYQNADYADQYQLFVSRVRAAEASL
GKATLTEAVARNLFKLMAYKDEYEVARLHSDPAFHARLASQFEGDFKLKVHLAPPLIAKK
NERGELVKQPFGPFMFKVFKVLARFKGLRGTPLDLFGRTEERRTERALIGQYRADVETLL
AGLNSTNHALALEIAGLPEQIKGFGHVKERNLAAARSRREALLQQWRQPRSAPSLARAA