Protein Info for GFF2545 in Variovorax sp. SCN45

Annotation: Ubiquinone biosynthesis regulatory protein kinase UbiB

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 521 signal peptide" amino acids 1 to 21 (21 residues), see Phobius details transmembrane" amino acids 497 to 516 (20 residues), see Phobius details TIGR01982: 2-polyprenylphenol 6-hydroxylase" amino acids 6 to 444 (439 residues), 548.7 bits, see alignment E=4e-169 PF03109: ABC1" amino acids 89 to 342 (254 residues), 236.6 bits, see alignment E=1.2e-74

Best Hits

Swiss-Prot: 94% identical to UBIB_VARPS: Probable protein kinase UbiB (ubiB) from Variovorax paradoxus (strain S110)

KEGG orthology group: K03688, ubiquinone biosynthesis protein (inferred from 95% identity to vpe:Varpa_4796)

Predicted SEED Role

"Ubiquinone biosynthesis monooxygenase UbiB" in subsystem Ubiquinone Biosynthesis

MetaCyc Pathways

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (521 amino acids)

>GFF2545 Ubiquinone biosynthesis regulatory protein kinase UbiB (Variovorax sp. SCN45)
MRRFYRGLFIVWVALRYGLDELVLTSFQKPWLRVVARIVSFGRNLDAPRGQRLREALERL
GPIFVKFGQVLSTRRDLLPPDIADELAFLQDRVPPFPSSVAIATIERAFRRPVGDVFVQF
DETPIASASIAQVHFATIRTNAGELREVAVKVLRPNMRGVIEKDLALMAMMAGWVEGLSA
DGKRLKPREVVGEFDKYLHDELDLVREAANAAQLRRNMSELDLVLIPEMFWDFCHPEVIV
MERMKGVPIAQMDRLRAAGVDIPKLARDGVTIFFTQVFRDGFFHADMHPGNIQVSLEPET
FGRYISLDFGIIGTLTESDKEYLAQNFVAFFRRDYKRVAELHLESGWVPVGTRIDELEAA
IRTVCEPYFDRPLKELSLGMVLMRLFQTSRRFQVEIQPQLVLLQKTLLNIEGLGRNIDPD
LDLWATAKPFLEKWMVDQIGPKKLLQQLKAEAPRYAKLLPQFPRLLHDFLENRPADNRRE
LLELLAEQKRTNRLLQTIVYGGIGFVLGLLAMQLLVRVRLF