Protein Info for GFF2528 in Methylophilus sp. DMC18

Annotation: hypothetical protein

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 378 transmembrane" amino acids 12 to 36 (25 residues), see Phobius details amino acids 144 to 169 (26 residues), see Phobius details amino acids 191 to 213 (23 residues), see Phobius details amino acids 337 to 357 (21 residues), see Phobius details PF03929: PepSY_TM" amino acids 10 to 360 (351 residues), 196.1 bits, see alignment E=6.3e-62

Best Hits

KEGG orthology group: None (inferred from 61% identity to del:DelCs14_4760)

Predicted SEED Role

"putative iron-regulated membrane protein"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (378 amino acids)

>GFF2528 hypothetical protein (Methylophilus sp. DMC18)
MKQQTIRRWAWIHKWSSLVCTAFMLLLCLTGLPLIFMHELHHLLGDQIETPVISHAGPNA
SMDSLMVAAKARYPKLVPQYMYREDDEPLQWVVRLGATPTDITNTHNVVLDARTAQVLGE
PKDDEGFLYVMFKLHVDLFAGLPGMLFLGLMGFLLLIALISGVVLYAPFMRKLPFGEIRH
QRGDKLKRLDIHNFLGIVTLCWLLVVGATGVINTWSDLLIKYWQFDQMAQMVAPYKNLPP
PTAFASLQQSLQVAQRAEPEMELGFIAFPGTPYTSQHHYGIFMRGDSPLTKRLFKPVLID
AQTAQLTDSRPLPWYLVGLLVSQPLHFGDYGGMTLKWIWAVLDILSIVVLWTGLKLWWKK
RHQYVPDIQTRIILSEAS