Protein Info for GFF2520 in Xanthobacter sp. DMC5

Annotation: Vitamin B12 import ATP-binding protein BtuD

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 550 600 650 700 750 800 841 signal peptide" amino acids 1 to 27 (27 residues), see Phobius details transmembrane" amino acids 36 to 54 (19 residues), see Phobius details amino acids 61 to 77 (17 residues), see Phobius details amino acids 83 to 105 (23 residues), see Phobius details amino acids 111 to 131 (21 residues), see Phobius details amino acids 158 to 177 (20 residues), see Phobius details amino acids 205 to 227 (23 residues), see Phobius details amino acids 245 to 270 (26 residues), see Phobius details amino acids 281 to 305 (25 residues), see Phobius details PF02653: BPD_transp_2" amino acids 29 to 295 (267 residues), 122.3 bits, see alignment E=6.5e-39 PF00005: ABC_tran" amino acids 371 to 520 (150 residues), 76.3 bits, see alignment E=1.1e-24 amino acids 626 to 770 (145 residues), 108.6 bits, see alignment E=1.2e-34

Best Hits

KEGG orthology group: None (inferred from 86% identity to xau:Xaut_0428)

Predicted SEED Role

"ABC transporter ATP-binding/permease protein"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (841 amino acids)

>GFF2520 Vitamin B12 import ATP-binding protein BtuD (Xanthobacter sp. DMC5)
MLARNANLIVAAAALAVLPALLSALGLTVTSATDVVILALACMALNLLVGYTGLVSFGHG
AWFGLGAYAAALIQQRLFPEWGLALAIPAAVVVTLAAIPVGYVVLRRRGVYFSLLTLALT
ALAYTVAFRWTAVTGGENGLGGVNRGPFLGLDVDRNATFYWVVAGAAFLIILTLQRFVRS
PVGTVLVAIRENEQRARFIGYDTRAYKIACFTLSAGLTAFAGALLAFNHRFASADPIAIA
FSGELLAMVVIGGMRSFLGPALGALFFVLFREFLSMWTANWLFWFGLLFMAFIVFSPTGL
VGVAGRLLAPLRKKTIEAAAMGRRTSAERRPLPSSLTARARWESSAPLLEAKNLALGFGA
IKAVRSGAVAVKDRTLHALIGPNGAGKTSTFNMISGMFPPNSGEIRLAGERIDGLSPNAV
CMKGLARSFQITNLFPTLSVEENLRLGVQATHKSRLNPWRDAAGIPEINAETAEMVAFLG
VAGMERAEAGALSYGGQRLLDMGLALTSRPRVLLLDEPLAGLAAAERNRVSNLIKDISAE
VPVLLVEHDIDRVFELADAVTVMADGAVLVDGTVEDARSDKRVQEVYIGSGAAALAARDL
ESAATDTVMLRLHGIDAFYGKSRILAGVSLEAKEGEILALLGRNGAGKSTLLKAITGIVK
PMNGSLTLAGEELMGLSSAAIARRGVGYVPQGRALFHGMSVRHNLELGRLKRITGAGKHF
SEEEVLDLFPRLKVRMDTPADLLSGGEQQMVAVARALMGDTRVLLLDEPFEGLSPAVTEE
LFDAFDRLRRSLTLVIVDHHLDVVLNLADRAVVLERGEVVHEGPARPLARDLDLRRQVLW
L