Protein Info for GFF2504 in Sphingobium sp. HT1-2

Annotation: Na(+)-dependent bicarbonate transporter BicA

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 498 transmembrane" amino acids 14 to 35 (22 residues), see Phobius details amino acids 43 to 63 (21 residues), see Phobius details amino acids 83 to 103 (21 residues), see Phobius details amino acids 115 to 136 (22 residues), see Phobius details amino acids 164 to 181 (18 residues), see Phobius details amino acids 192 to 214 (23 residues), see Phobius details amino acids 238 to 263 (26 residues), see Phobius details amino acids 284 to 304 (21 residues), see Phobius details amino acids 316 to 336 (21 residues), see Phobius details amino acids 342 to 361 (20 residues), see Phobius details amino acids 373 to 401 (29 residues), see Phobius details PF00916: Sulfate_transp" amino acids 10 to 379 (370 residues), 204.5 bits, see alignment E=1.1e-64

Best Hits

KEGG orthology group: None (inferred from 90% identity to sch:Sphch_1387)

Predicted SEED Role

"Sulfate transporter family protein in cluster with carbonic anhydrase"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (498 amino acids)

>GFF2504 Na(+)-dependent bicarbonate transporter BicA (Sphingobium sp. HT1-2)
MLKAFSGGTFSRDFTASIVVFLVAMPLCMGIAIASGVPPEKGLITGIIGGLVVGLLAGSP
LQVSGPAAGLAVIVFEIVREQGLSALGPILILAGAIQIVAGLLKVGGWFRAISPAVVHGM
LAGIGVLIVVGQFHVLFDDKPLSSGLHNLIAMPGQILGLTNQDAATAFAVGLVTIGAMLG
WEKFRPASMKLVPGALVGVVAATLVAFALGLPVARVVVPESILSAISLPEQGLLAQLMSP
TIITTAIAIAFIASAETLLSAAAVDRMHDGVRTNYNRELSAQGVGNLLCGVAGALPMTGV
IVRSSANVQAGAKTRLSAILHGAWILGFVALLPWLLREVPMAALAGILVVTGFRLVSLSH
VKHLFHLYGPLPAIVWAATLICVVATDLLTGVLVGIGLSLIELIPHASRLRLGVEEASRG
DAHEVALHGTASFLSLPKLSAKLESVPAGQLVILNVERLTHIDHTCAEMVREWADRRTGA
GAKVELFGATGRMRQLVA