Protein Info for PS417_12690 in Pseudomonas simiae WCS417

Annotation: xylulose kinase

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

• PF00370: FGGY_N
  • amino acids 7 to 255 (249 residues), 240.6 bits, E=2e-75
• TIGR01312: xylulokinase
  • amino acids 8 to 490 (483 residues), 636.4 bits, E=1.3e-195
• PF02782: FGGY_C
  • amino acids 325 to 447 (123 residues), 91.7 bits, E=5.6e-30

Best Hits

Swiss-Prot: 55% identical to XYLB_HAEIN: Xylulose kinase (xylB) from Haemophilus influenzae (strain ATCC 51907 / DSM 11121 / KW20 / Rd)

KEGG orthology group: K00854, xylulokinase [EC: 2.7.1.17] (inferred from 96% identity to pfs:PFLU2740)

MetaCyc: 71% identical to xylulose kinase (Pseudomonas fluorescens)
Xylulokinase. [EC: 2.7.1.17]

Predicted SEED Role

"Xylulose kinase (EC 2.7.1.17)" in subsystem Ribitol, Xylitol, Arabitol, Mannitol and Sorbitol utilization or Xylose utilization (EC 2.7.1.17)

MetaCyc Pathways

• superpathway of glucose and xylose degradation (16/17 steps found)
• D-xylose degradation I (2/2 steps found)
• xylitol degradation I (2/2 steps found)
• D-arabinitol degradation I (1/2 steps found)
• superpathway of pentose and pentitol degradation (16/42 steps found)

KEGG Metabolic Maps

• Pentose and glucuronate interconversions

Isozymes

Compare fitness of predicted isozymes for: 2.7.1.17

Use Curated BLAST to search for 2.7.1.17

Sequence Analysis Tools

See A0A1N7U3B6 at UniProt or InterPro

Protein Sequence (493 amino acids)

>PS417_12690 xylulose kinase (Pseudomonas simiae WCS417)
MTQQNLFLGIDCGTQGTKAIVLDASSGKVLGLGAAAHTLISGANGRREQHTQEWLDAFTE
ATHRALQQAGVDGQDILGIGVSGQQHGLVLLDDQGRVLRPAKLWCDTETAPENERLLQHL
GGESGSLERLGVAIAPGYTVSKLLWTREQHPDIFARITHILLPHDYLNYWLTGRAVAEYG
DASGTGYFNVRTREWDVALLKHIDPSGRLENALPQLIEADQSVGTILPAIAERLGINPNA
IVSSGGGDNMMGAIGTGNIAPGVITMSLGSSGTVYAFADQPSVSPQASVATFCSSSGGWL
PLICTMNLTNATGVIRELFDLDLTAFNALVEQAPIGADGVSMLPFLNGERVPALPHATGS
LHGLTMTNLTRANLCRAVVEGTTFGLRYGLDLLRQTGLQSQSIRLIGGGSKSPIWRQMVA
DIMNTEVVCTEQSEAAALGAAIQAAWSQSGESLASLCDKCVSVDPASRTLPVAASVSAYQ
QAYERYQQLVATL