Protein Info for GFF2482 in Salmonella enterica subsp. enterica serovar Typhimurium str. MS1868

Annotation: Anaerobic dimethyl sulfoxide reductase chain A (EC 1.8.99.-)

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 550 600 650 700 750 811 signal peptide" amino acids 1 to 46 (46 residues), see Phobius details TIGR02166: anaerobic dimethyl sulfoxide reductase, A subunit, DmsA/YnfE family" amino acids 14 to 811 (798 residues), 1281.3 bits, see alignment E=0 PF04879: Molybdop_Fe4S4" amino acids 56 to 115 (60 residues), 48.2 bits, see alignment 1.3e-16 PF00384: Molybdopterin" amino acids 118 to 569 (452 residues), 209.5 bits, see alignment E=1.2e-65 PF01568: Molydop_binding" amino acids 690 to 803 (114 residues), 92.3 bits, see alignment E=3e-30

Best Hits

Swiss-Prot: 92% identical to YNFF_ECOLI: Probable dimethyl sulfoxide reductase chain YnfF (ynfF) from Escherichia coli (strain K12)

KEGG orthology group: K07310, Tat-targeted selenate reductase subunit YnfF [EC: 1.97.1.9] (inferred from 93% identity to cko:CKO_01582)

MetaCyc: 65% identical to dimethyl sulfoxide reductase subunit A (Escherichia coli K-12 substr. MG1655)
DIMESULFREDUCT-RXN [EC: 1.8.5.3]

Predicted SEED Role

No annotation

MetaCyc Pathways

Isozymes

Compare fitness of predicted isozymes for: 1.8.5.3, 1.97.1.9

Use Curated BLAST to search for 1.8.5.3 or 1.97.1.9

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (811 amino acids)

>GFF2482 Anaerobic dimethyl sulfoxide reductase chain A (EC 1.8.99.-) (Salmonella enterica subsp. enterica serovar Typhimurium str. MS1868)
MKITNPEALMAASLSRRSLVKTSAIGSLALASSAFTLPFSRIAHAAADLASGNVAEKAVW
SSCTVNCGSRCLLRLHVKDDTVYWVESDTTGNDEYGNHQVRACLRGRSIRRRMNHPDRLK
YPMKRVGKRGEGKFERISWDEALDTIGDNLKRILKDYGNEAVHVLYGTGVDGGNITNSNV
PYRLMNACGGYLSRYGSYSTAQISAAMSYMFGGNDGNSPDDIANTKLVVMFGNNPAETRM
SGGGVTYYVEQARERSNARMIVIDPRYNDTAAGREDEWLPIRPGTDGALAAAIAWVLITE
DLIDKPFLDKYCIGYDETTLPASAPRNAHYKAYILGQGDDGIAKTPQWAAQITSIPAEKI
IQLAREIGSAKPAYICQGWGPQRHSNGEQTARAIAMLSVLTGNVGINGGNSGVREGTWDL
GVEWFSMLENPVKTQISVFTWTDAIDHGAEMTATRDGVRGKDKLDVPIKFLWCYASNTLI
NQHGDIAHTHEVLQDDSKCEMIVGIEHFMTASAKYCDILLPDLMPTEQEDLISHESAGNM
GYVILGQPATSPKFERKPIYWTLSEVAKRLGPDVYQTFTEGRTQHEWVKYLHAKTKARNP
EMPDYEEMKQTGIFKKKCPEEHYVAFRAFREDPAANPLKTPSGKIEIYSERLATLANTWE
LKKDEIIHPLPAYTPGFDGWDDPLRQRYPLQLTGFHYKARTHSSYGNIDILQQACPQEIW
INPIDAQARGIQHGDTVRVFNQNGEMLIPAKVTPRILPGVTAIGQGAWLNADMFGDKVDR
GGSINILTSHRPSPLAKGNPSHSNLVQVEKA