Protein Info for GFF2458 in Hydrogenophaga sp. GW460-11-11-14-LB1

Annotation: putative membrane protein

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 391 signal peptide" amino acids 1 to 23 (23 residues), see Phobius details transmembrane" amino acids 24 to 24 (1 residues), see Phobius details amino acids 37 to 59 (23 residues), see Phobius details amino acids 71 to 89 (19 residues), see Phobius details amino acids 95 to 118 (24 residues), see Phobius details amino acids 130 to 149 (20 residues), see Phobius details amino acids 160 to 181 (22 residues), see Phobius details amino acids 206 to 226 (21 residues), see Phobius details amino acids 243 to 262 (20 residues), see Phobius details amino acids 264 to 265 (2 residues), see Phobius details amino acids 271 to 291 (21 residues), see Phobius details amino acids 297 to 321 (25 residues), see Phobius details amino acids 333 to 354 (22 residues), see Phobius details amino acids 361 to 382 (22 residues), see Phobius details PF07690: MFS_1" amino acids 7 to 244 (238 residues), 51.9 bits, see alignment E=2.8e-18 amino acids 251 to 386 (136 residues), 45.3 bits, see alignment E=3e-16

Best Hits

Swiss-Prot: 37% identical to RFNT_OCHA4: Riboflavin transporter RfnT (rfnT) from Ochrobactrum anthropi (strain ATCC 49188 / DSM 6882 / JCM 21032 / NBRC 15819 / NCTC 12168)

KEGG orthology group: None (inferred from 75% identity to tmz:Tmz1t_1945)

Predicted SEED Role

"putative membrane protein"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (391 amino acids)

>GFF2458 putative membrane protein (Hydrogenophaga sp. GW460-11-11-14-LB1)
MNKNLWLLAGAQGLFLTNNVVFIAINGLVGLALAPLGWMATLPVMGYVVGGALSTPLVAR
TQSAFGRKASFQIGLLVALASALLCAWAAMDRNFWLLVAATVIAGYYSANGQLYRFAAAE
LSAPAFRDKAVSLVLAGGLIGAVLGPNLAVRTKDWLGVPFAGAYVALAVVAVLSMGLMAF
LRFPPAPPVAAGADRGRPLSEIVRQPVFLVAAAGAALGYGVMNLLMAATPLAMQVCGFAF
DDAALVLEWHVIGMFAPGFFTGHLIARFGTLTIMGVGVLLNLLCIAVALSGVDLHQFLIA
LFLLGVGWNFLFTGSTTLALQAYRPEEKNRAQAAINFCVFATMALTSFASGALVTTQGWQ
WLNIGSLVPVGLTGLALIWLAWVRRQAHNPA