Protein Info for PS417_12430 in Pseudomonas simiae WCS417

Annotation: TonB-dependent receptor

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 550 600 650 700 742 signal peptide" amino acids 1 to 27 (27 residues), see Phobius details PF07715: Plug" amino acids 72 to 168 (97 residues), 58.7 bits, see alignment E=7.8e-20 TIGR01783: TonB-dependent siderophore receptor" amino acids 74 to 737 (664 residues), 335.3 bits, see alignment E=4.4e-104 PF00593: TonB_dep_Rec_b-barrel" amino acids 274 to 711 (438 residues), 162.8 bits, see alignment E=2.7e-51

Best Hits

KEGG orthology group: K02014, iron complex outermembrane recepter protein (inferred from 80% identity to pfs:PFLU2688)

Predicted SEED Role

"Outer membrane receptor for ferric coprogen and ferric-rhodotorulic acid" in subsystem Ton and Tol transport systems

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See A0A1N7U372 at UniProt or InterPro

Protein Sequence (742 amino acids)

>PS417_12430 TonB-dependent receptor (Pseudomonas simiae WCS417)
MFAPFTRSMTFTLGLFTVVASPDLLAETDPENNALELGATSITAEGLGATTEHTGAYTTG
SMSTATRLNLSVKDTPQSISVITRQQMDDFNLNTLTDALRQTTGVTVQHLDSDRAGYSSR
GYSINNFQVDGMLNTFGRMKSDADTIIYDRIEVVRGATGLTTGAGDPSATVNMIRKRPTS
QWQAKAGVSGASHDNYYSYLDVGGPLAFDGRLRGRTVMAYRDSQSFRDNYALQREVGYGI
LEADLTDDTVVAVGFDYQNKHVQGTSWGTLPYWNSDGGKARLSRSANMATDWSSWPLKDK
TTFASLDHKLSEDWRLKAAYTHRQSDTDGKVYYGGAGFPNPDGSGMTAWTNQMVGTSKMD
AVDFNLAGTYTLLGREHELMVGYGESEQRDSSPYQRYSTPEGYETIPDWQDMGGIVKFPD
RTTGLKGPHSSKQQKAGYLATRLSLTDRLHAVLGSRYGSWEIESTPVDYDANNQRIPEPK
TRQTHNDMWTPYAGLLYDLTPQYTVYASYTDIFNPQDERDASKKYLEPVVGSNYEIGLKG
SLLNERLNLATAYFWSTQDNVAELDNAAPPDPVTREQFYKSGGKGNKVQGFEVEVSGEVM
PDWNLTAGYTYTHSVNGDKQRNNTDQPMNLLKMSTAYRLPGEWRGLTVGGAVNWQSEFYK
FAGRPTGGRNQDGDLITTPTKITQQAYTVVNLMSRYQFDEHVSASINVNNLFDKKYYERV
GFYNGVYWGDPRSITLALDWKL