Protein Info for GFF2438 in Variovorax sp. SCN45

Annotation: Ferrichrome-iron receptor

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 550 600 650 700 750 818 signal peptide" amino acids 1 to 39 (39 residues), see Phobius details PF07660: STN" amino acids 80 to 124 (45 residues), 33.8 bits, see alignment 3.5e-12 PF07715: Plug" amino acids 168 to 271 (104 residues), 85.8 bits, see alignment E=4.2e-28 TIGR01783: TonB-dependent siderophore receptor" amino acids 170 to 817 (648 residues), 359 bits, see alignment E=2.9e-111 PF00593: TonB_dep_Rec_b-barrel" amino acids 345 to 788 (444 residues), 218.3 bits, see alignment E=5.8e-68

Best Hits

KEGG orthology group: K02014, iron complex outermembrane recepter protein (inferred from 74% identity to del:DelCs14_3621)

Predicted SEED Role

"Ferrichrome-iron receptor" in subsystem Iron acquisition in Vibrio or Transport of Iron

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (818 amino acids)

>GFF2438 Ferrichrome-iron receptor (Variovorax sp. SCN45)
MTQQHHGAQRFRADSFPLAALACAVASALLVMGGTAHAQEASASPPSAPTAVSLSLPSQP
LAQALGVLSRQYGTAIGGESSLLEGRTAPAVRGTVTLQQALERVLAGSGLTVVRSGASGF
TVIRAAAAGTTTLAPVTVTADAEETATAHMPGYIARRNTTGSKTDTPIIETPQSISVVTA
DFIEATGATRLKEALAYTPGINVSPWGADSRFDWTILRGFDAQAPGYYLDGLQLRNNNGW
AIWQTESYGTERVEVLRGPSSVLYGQNGPGGMINVVSKRPTEEPLHELQVQFGDNARRQI
AGDFSGPLDAEGKVLYRLTGLVRDAKLPASGLPNDRTFLAPALTWKPSGDTTLTVLSHYL
RVRDGSSYGSFPEVGTLLPNPNGRFSPKTYVGDPNFDRFNQDQWMLGYLLEHRLNDTFTF
RQNARIGSNKVDYGQVFNQPNFVTVDPDNADSPANYRVLSRFPFASKEKSRIASIDNQLQ
ARLHWGDWQHTLLFGLDYQRSRNDQRTSNSGTVPDIDGYLPVHEGFVTTADPWFDARTTL
SQTGFYMQDQIKWGDWVATLGGRYDSARAVSYSHIDGSTTRVSDHKFTSRAGLVYLHPSG
WAPYFSYSESFSPTVTIDPQTQQPLKPETGRQYEVGVRYQPAGRKDKYSAAVFDLRRQNY
ITYDADFVPKQTGEILVRGLELEASFEPMPRMNVTAAYTYTPKAVVTASSTASDIGKQMQ
AVSRNQLSVWADYRFSNGVKTGLGVRFMGSNRGYQESTKVPVPSYAVFDALVGYDFERWN
LALNLRNLGNKTYVANCSSGSCYYGEPRKVLVTATYRW