Protein Info for PS417_12290 in Pseudomonas simiae WCS417

Annotation: sulfite reductase

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

• PF03460: NIR_SIR_ferr
  • amino acids 53 to 109 (57 residues), 58.1 bits, 5.8e-20
  • amino acids 343 to 398 (56 residues), 43.5 bits, 2.2e-15
• PF01077: NIR_SIR
  • amino acids 119 to 272 (154 residues), 163.7 bits, E=2.3e-52
  • amino acids 411 to 547 (137 residues), 53.5 bits, E=2e-18

Best Hits

KEGG orthology group: K00381, sulfite reductase (NADPH) hemoprotein beta-component [EC: 1.8.1.2] (inferred from 100% identity to pfs:PFLU2657)

Predicted SEED Role

"Sulfite reductase [NADPH] hemoprotein beta-component (EC 1.8.1.2)" in subsystem Cysteine Biosynthesis (EC 1.8.1.2)

MetaCyc Pathways

• superpathway of L-methionine biosynthesis (by sulfhydrylation) (12/12 steps found)
• superpathway of sulfate assimilation and cysteine biosynthesis (9/9 steps found)
• assimilatory sulfate reduction I (4/4 steps found)
• assimilatory sulfate reduction III (3/3 steps found)
• superpathway of sulfur amino acid biosynthesis (Saccharomyces cerevisiae) (7/10 steps found)

KEGG Metabolic Maps

• Sulfur metabolism

Isozymes

Compare fitness of predicted isozymes for: 1.8.1.2

Use Curated BLAST to search for 1.8.1.2

Sequence Analysis Tools

See A0A1N7TYZ7 at UniProt or InterPro

Protein Sequence (552 amino acids)

>PS417_12290 sulfite reductase (Pseudomonas simiae WCS417)
MYVYDEYDQRIIEDRVKQFRDQTRRYLAGELSEEEFRPLRLQNGLYVQRFAPMLRVAVPY
GQLTSRQTRMMAKIARDFDKGYAHISTRQNVQFNWPALEDVPDILAELATVQMHAIQTSG
NCLRNVTTDQFAGVAADELIDPRPWCEIVRQWTTFHPEFAYLPRKFKIAINGSTSDRAAI
EVHDIGLEPVHNEAGELGFRVLVGGGLGRTPVVGAFINEFLPWQDLLSYLDAILRVYNRY
GRRDNKYKARIKILVKALTPEVFAQKVDAEMEYLRGGQTTLTEAEVHRVAKHFVDPEYKA
LSNQDAELSALDKEHPGFARWRTRNTLAHKKPGYVAVTLSLKPTGVAPGDITDKQLDAVA
DLAERYSFGQLRTSHEQNIILADVEQSQLFTLWGELREGGFATPNIGLLTDIICCPGGDF
CSLANAKSIPIAESIQRRFDDLDYLFDIGELDLNISGCMNACGHHHVGHIGILGVDKKGE
EFYQVSLGGSASRDASLGKILGPSFAQEAMPEVIGKLIDVYIEQRTEDERFIDTYQRIGI
DLFKERVYAANH