Protein Info for PS417_12275 in Pseudomonas simiae WCS417

Annotation: 2,4-dienoyl-CoA reductase

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 410 transmembrane" amino acids 281 to 298 (18 residues), see Phobius details PF00724: Oxidored_FMN" amino acids 4 to 340 (337 residues), 173.4 bits, see alignment E=4.2e-55

Best Hits

KEGG orthology group: None (inferred from 95% identity to pfs:PFLU2654)

Predicted SEED Role

"2,4-dienoyl-CoA reductase [NADPH] (EC 1.3.1.34)" (EC 1.3.1.34)

Isozymes

Compare fitness of predicted isozymes for: 1.3.1.34

Use Curated BLAST to search for 1.3.1.34

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See A0A1N7U349 at UniProt or InterPro

Protein Sequence (410 amino acids)

>PS417_12275 2,4-dienoyl-CoA reductase (Pseudomonas simiae WCS417)
MSPFEALQLPNGQVLPNRIAKAAMEENMADGNQAPSRELKQLYKAWADGKPGVLITGNVM
VDRRAMTGPGGVALEDEQHLASFREWADVARSNGVHFWVQLSHPGRQTPANLRQQALAPS
AVALDLGGFSKMFATPKAMTEDDIQDVIQRFATSARLAEKAGFTGVQIHGAHGYLLSQFL
SPLSNQRTDRWGGSLENRARLLLDVIRAVRANVSPAFCVSVKLNSADFQRGGFAEADARA
VVEMLNPLPIDLLELSGGSYEAPAMQGEARDGRTLAREAYFLEFASQLATIATMPLLVTG
GIRRLPIVQQVLDSGVAMAGIATALTLEPQLIQHWREGRDPNPQLKPIDWKRKPLASLAI
LAVVRYQMRRLSRGHLPKANVAPCMALVRDQWFLARRTRQYRAAMTQSSH