Protein Info for GFF2405 in Hydrogenophaga sp. GW460-11-11-14-LB1

Annotation: L-carnitine dehydratase/bile acid-inducible protein F (EC 2.8.3.16)

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

• PF02515: CoA_transf_3
  • amino acids 10 to 366 (357 residues), 388.2 bits, E=2e-120

Best Hits

Swiss-Prot: 39% identical to ACOCT_ECOLI: Acetyl-CoA:oxalate CoA-transferase (yfdE) from Escherichia coli (strain K12)

KEGG orthology group: None (inferred from 73% identity to reh:H16_B0089)

MetaCyc: 39% identical to acetyl-CoA:oxalate CoA-transferase (Escherichia coli K-12 substr. MG1655)
RXN0-7075 [EC: 2.8.3.19]

Predicted SEED Role

"L-carnitine dehydratase/bile acid-inducible protein F (EC 2.8.3.16)" (EC 2.8.3.16)

MetaCyc Pathways

• oxalate degradation II (1/3 steps found)

Isozymes

Compare fitness of predicted isozymes for: 2.8.3.16

Use Curated BLAST to search for 2.8.3.16 or 2.8.3.19

Protein Sequence (366 amino acids)

>GFF2405 L-carnitine dehydratase/bile acid-inducible protein F (EC 2.8.3.16) (Hydrogenophaga sp. GW460-11-11-14-LB1)
MPIPLSTGALHGIRVIDLSRVLGGPYCGQILGDHGADVLKVEPPQGDETRTWGPPFEPDG
VASYYKGLNRNKRGVRIDLASDSGREQLLTLLEGADVLLENFKTGTLERWGIGYGTLSQR
FPRLVHCRVSGYGADGPLGGLPGYDAAIQALTGIMSVNGETGGDALRVGIPVVDMVTGLN
AAIGVLLALHERERSGLGQFVETALFDCGLSLLHPHAANLFGGGRTPARTGNAHPNIYPY
DAFPTRSIPIFLAVGNDGQFRKLCEQLGAPALASRPAFANAGARSENREALRSELVTLLS
GVDGDALVDRLSEAGVPCAPILDVAQALSHPHTQHRGMTVQVDGYRGMASPIKLGRTPAT
YRLVPP