Protein Info for PS417_12215 in Pseudomonas simiae WCS417

Annotation: lytic transglycosylase

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 471 signal peptide" amino acids 1 to 35 (35 residues), see Phobius details PF06474: MLTD_N" amino acids 1 to 34 (34 residues), 56.6 bits, see alignment 3.5e-19 PF01464: SLT" amino acids 127 to 227 (101 residues), 92.3 bits, see alignment E=2.3e-30 PF01476: LysM" amino acids 367 to 407 (41 residues), 46.2 bits, see alignment 5.4e-16 amino acids 426 to 467 (42 residues), 39.1 bits, see alignment 9e-14

Best Hits

KEGG orthology group: K08307, membrane-bound lytic murein transglycosylase D [EC: 3.2.1.-] (inferred from 98% identity to pfs:PFLU2642)

Predicted SEED Role

"Membrane-bound lytic murein transglycosylase D precursor (EC 3.2.1.-)" (EC 3.2.1.-)

KEGG Metabolic Maps

Isozymes

Compare fitness of predicted isozymes for: 3.2.1.-

Use Curated BLAST to search for 3.2.1.-

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See A0A1N7TX64 at UniProt or InterPro

Protein Sequence (471 amino acids)

>PS417_12215 lytic transglycosylase (Pseudomonas simiae WCS417)
MSSSIRKSNHSDALTRLAQAVAVAVSATLAGCQSSNFTAQSTVQPKPNLTAKIKQKPVIW
LSDKPAPEVPQDVWERMRRGFQLQDGVGVNPRIEQQRLWFASNPSFLENAGERGSLYIHY
IVERLEERNMPLELALLPVIESAYNPMAYSRSDAVGLWQFIPSTGRYFNLRQTRAYDGRR
DITASTTAALDYLTRLHDMFNGDWLLALAAYNAGEGTVSRAIERNEKLGLPTDYWNLPLP
QETKDYVPKFLALSQVVLAPEAYGVNLNPIANTPYFEVVEVKQSMDLSRVAALAEIDEDE
LFQLNPALKQRTTLDGPQHLLVPSSKAQLLTSTLSTMKPEELLAMRPKKQVFDEVETARV
AGRTRNYKVRSGDNLTLIAKANKVDVHDLQRWNKLNGQALKVGQTLVMQDTRKRVAKADS
KKPVQYKVKKGDSLYIVAKRFNVEMQHLKRWNPRTGQALKPGQMLVVSGPR