Protein Info for GFF239 in Variovorax sp. SCN45

Annotation: DNA polymerase III chi subunit (EC 2.7.7.7)

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 146 PF04364: DNA_pol3_chi" amino acids 2 to 138 (137 residues), 109.5 bits, see alignment E=7.6e-36

Best Hits

KEGG orthology group: K02339, DNA polymerase III subunit chi [EC: 2.7.7.7] (inferred from 89% identity to vpe:Varpa_2830)

Predicted SEED Role

"DNA polymerase III chi subunit (EC 2.7.7.7)" in subsystem DNA-replication (EC 2.7.7.7)

KEGG Metabolic Maps

Isozymes

Compare fitness of predicted isozymes for: 2.7.7.7

Use Curated BLAST to search for 2.7.7.7

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (146 amino acids)

>GFF239 DNA polymerase III chi subunit (EC 2.7.7.7) (Variovorax sp. SCN45)
VTEIGFHYNAPDKLNYACRLVRKAVNARGLRVVVIGDARALDVVDAALWQLSPVDFVAHC
RGDAPPHVLARTPVILSSDGADAAALPHREMLVNLGLEVPAGFERYERLIDIVSDESNDR
QVGRSRWRHYADRGYTIQPHDFAKSS