Protein Info for GFF239 in Hydrogenophaga sp. GW460-11-11-14-LB1

Annotation: NAD(P)H-flavin oxidoreductase

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 195 PF01613: Flavin_Reduct" amino acids 21 to 159 (139 residues), 70.9 bits, see alignment E=6.8e-24

Best Hits

Swiss-Prot: 42% identical to YDDH_ECOLI: Uncharacterized protein YddH (yddH) from Escherichia coli (strain K12)

KEGG orthology group: None (inferred from 71% identity to ctt:CtCNB1_4672)

Predicted SEED Role

"NAD(P)H-flavin oxidoreductase"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (195 amino acids)

>GFF239 NAD(P)H-flavin oxidoreductase (Hydrogenophaga sp. GW460-11-11-14-LB1)
MPLPHFTPVALDKAYRLINHGPTVLVSSAHAGEVNVMSAAWACALDFSPPKVTVVIDKAT
RTRALVEGSGAFALCVPPVGLAALAFGVGSDSALTVPDKLARHGVKTFHAPGHEALPLVE
GCVAWLACRLIPEPHNQTAYDLFIGEVVGAWADERVFRAGRWHFDGAPDQLRTLHYVAGG
QFYATGASLQVGGGQ