Protein Info for GFF2376 in Pseudomonas sp. DMC3

Annotation: Outer membrane efflux protein BepC

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 452 signal peptide" amino acids 1 to 24 (24 residues), see Phobius details TIGR01844: type I secretion outer membrane protein, TolC family" amino acids 22 to 430 (409 residues), 291.4 bits, see alignment E=6.2e-91 PF02321: OEP" amino acids 26 to 218 (193 residues), 64.5 bits, see alignment E=5.9e-22 amino acids 239 to 409 (171 residues), 99.7 bits, see alignment E=9.7e-33

Best Hits

KEGG orthology group: K03287, outer membrane factor, OMF family (inferred from 96% identity to pfo:Pfl01_1462)

Predicted SEED Role

"Agglutination protein"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (452 amino acids)

>GFF2376 Outer membrane efflux protein BepC (Pseudomonas sp. DMC3)
MRVLTPLCSAVLLAMACTSQAQAMNLTEAIQSTIATHPELASRVDARLSADEQVKVAKGG
FYPSVDLNAAYGRGYSDNTNTRAFGNHNTEILNYTQSELRLRQMIFDGFNTANEVERTKG
VSNSRAYYAQGTAQDLALRTIEVYLEVLKRRELVTLAKNNLQAHLRVNDQIGLRTERGIG
STADSDQSVARRALAQNNLDTAEVDLADAESNFYSVVGRMPDELETPASTRGEMPPDLRE
AQQSMVDNNPYLKSAQADVQSAESQYEVAKSPFYPRFDAEAAVGANNNVQGDEGHDNEWR
VGVVMNYNLFRGGSDKARLAANAHDINQAMDIRNNALRQLNENIRLAWNAMENAKKQTPT
AREYAETTKRVRAAYQDQFGLGQRTLLDLLDSENELYNANRRYTEIRYTEEYSMYRVLAN
MGQLLSKQRVVLPADAIATTEVKNQARLPELK