Protein Info for GFF237 in Variovorax sp. SCN45

Annotation: ABC-type branched-chain amino acid transport systems, periplasmic component

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 405 signal peptide" amino acids 1 to 37 (37 residues), see Phobius details PF13458: Peripla_BP_6" amino acids 53 to 396 (344 residues), 207.8 bits, see alignment E=5.9e-65 PF01094: ANF_receptor" amino acids 74 to 395 (322 residues), 116.8 bits, see alignment E=1.8e-37 PF13433: Peripla_BP_5" amino acids 183 to 380 (198 residues), 27.9 bits, see alignment E=1.9e-10

Best Hits

KEGG orthology group: K01999, branched-chain amino acid transport system substrate-binding protein (inferred from 94% identity to vpe:Varpa_2832)

Predicted SEED Role

"Leucine-, isoleucine-, valine-, threonine-, and alanine-binding protein"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (405 amino acids)

>GFF237 ABC-type branched-chain amino acid transport systems, periplasmic component (Variovorax sp. SCN45)
MQLKWTAVALAAITLVACGKKEEAAAPAAAPAPTAAAPAAAPAPAPAGDTLVVKIGHVAP
TSGPIAHLGKDNEMGAKMAIEDLNAKGIKIGDKTAKFELVAEDDAGDPKQGTAVAQKLVD
EKVNGVVGHLNSGTTIPASKLYSDAGIPQISPSATNPKYTRQGFKTTFRVVADDTQLGGT
LGKYAVETLKGKNIAVIDDRTAYGQGVAEEFEKSAKAAGATIVGHEFTTDKSTDFNAILT
KLKSAKPDVLFFGGMDAVGGPMLKQVKQLGLNVKFMGGDGLCTGELPKLAGDAIGEDMVV
CAEAGGVDGDFKQPLEDFKAKFKTKNGVEVQIYAPYVYDAVNVLAEAMVKAGSSDPEKYL
PEVGKVQYKGVTGPIAFDEKGDIKNGALTLYTYKGGARTQIAVVR