Protein Info for PS417_11935 in Pseudomonas simiae WCS417

Annotation: ABC transporter substrate-binding protein

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 338 signal peptide" amino acids 1 to 27 (27 residues), see Phobius details PF04069: OpuAC" amino acids 30 to 316 (287 residues), 194.4 bits, see alignment E=1.4e-61

Best Hits

KEGG orthology group: K02002, glycine betaine/proline transport system substrate-binding protein (inferred from 96% identity to pfs:PFLU2592)

Predicted SEED Role

"Histidine transporter, periplasmic histidine-binding protein"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See A0A1N7TYU9 at UniProt or InterPro

Protein Sequence (338 amino acids)

>PS417_11935 ABC transporter substrate-binding protein (Pseudomonas simiae WCS417)
MKGLKTLLAASLTTLGLSVAALPVSAAEAPVHFADLNWESGSLITEVLRVIVEKGYDLPT
DTLPGTTITLETALAKNDIQVIGEEWAGRSPVWVKAEAEGKVVGLGDTVKGATEGWWVPE
YVVKGDPAKGIKPLAPELKSVKDLARYKDVFKDPESPGKGRFLNSPIGWTSEVVNKQKLK
AYGLDDSYVNFRSGSGAALDAEIASSIRRGKPVLFYYWSPTPLMGRYKLIQLEEPPFDAE
AWKTLTDADNPNPKPTRSLASKLSIGVSTPFQKEHPQIAQFFEKVEFPIEPLNKALATMS
ENHTAPREVAQMFLKEHPQVWKAWLTEDVAQKVEASLK