Protein Info for GFF233 in Xanthobacter sp. DMC5

Annotation: hypothetical protein

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 265 signal peptide" amino acids 1 to 40 (40 residues), see Phobius details PF18312: ScsC_N" amino acids 44 to 74 (31 residues), 44.7 bits, see alignment 1.3e-15 PF13462: Thioredoxin_4" amino acids 96 to 255 (160 residues), 69.4 bits, see alignment E=6.4e-23 PF01323: DSBA" amino acids 110 to 256 (147 residues), 85.7 bits, see alignment E=5.6e-28

Best Hits

KEGG orthology group: None (inferred from 87% identity to xau:Xaut_3499)

Predicted SEED Role

"Protein-disulfide isomerase"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (265 amino acids)

>GFF233 hypothetical protein (Xanthobacter sp. DMC5)
MFSPTGLARTGFRHLAARLSALALAAVPAFFLAASPAAAFTDAEKKELGGIIREYLIQNP
EVLQEAISVLESRQMVADASQRSKAVAELKPLLLSSPRGIVAGNPQGDVTLVEFFDYNCG
YCKKALSDLQDLIKQDPKLRVVLKEFPVLGQGSVEAAQVAVAVRMVAPEKYMAFHQALLS
GRGQADRAKALAAAKEVGIDPALIQKQATSPELNATLDESMKIAEALSLNGTPSYVVGDQ
VVIGAVGFDKLKAAIAEARSKQAGK