Protein Info for GFF2325 in Hydrogenophaga sp. GW460-11-11-14-LB1

Annotation: Putative fumarylacetoacetate (FAA) hydrolase

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 317 PF01557: FAA_hydrolase" amino acids 109 to 313 (205 residues), 215.5 bits, see alignment E=3.6e-68

Best Hits

KEGG orthology group: None (inferred from 78% identity to bge:BC1002_5807)

Predicted SEED Role

"Putative fumarylacetoacetate (FAA) hydrolase" in subsystem Aromatic amino acid degradation

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

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Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (317 amino acids)

>GFF2325 Putative fumarylacetoacetate (FAA) hydrolase (Hydrogenophaga sp. GW460-11-11-14-LB1)
MVFPQKVRVDSPNLAVIKSRYSRFCNNVKTTGQPMRLVSFSRNGREGYGAVTDQGVVDLS
AVMGARFADLKALLAADALAEAATVAAQRAPDFALADAVLLPVIPNPGKIWCCGLNYGEH
VRETNREVTEQPTFFLRVADSQVGHDQAMVRPPESVQFDYEAEIAVVIGRPGRRIAEADA
GQHVAGYACYNDGSVRDWQRHTSQWVPGKNFWRTGGFGPWMVTADEIPFDTVMTLTTRLN
GVEMQRATTDMLIHSIARQIAYVSTIAPLEPGDVIVTGTPGGVGARRTPPVWMKAGDVCE
IEVDRVGVLRNPIADEA