Protein Info for PS417_11845 in Pseudomonas simiae WCS417

Annotation: RpiR family transcriptional regulator

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 302 transmembrane" amino acids 265 to 285 (21 residues), see Phobius details PF01418: HTH_6" amino acids 24 to 91 (68 residues), 48 bits, see alignment E=9.8e-17 PF01380: SIS" amino acids 157 to 282 (126 residues), 78.2 bits, see alignment E=5e-26

Best Hits

KEGG orthology group: None (inferred from 100% identity to pfs:PFLU2574)

Predicted SEED Role

"Predicted transcriptional regulator of the myo-inositol catabolic operon" in subsystem Inositol catabolism

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See A0A1N7U112 at UniProt or InterPro

Protein Sequence (302 amino acids)

>PS417_11845 RpiR family transcriptional regulator (Pseudomonas simiae WCS417)
MSRTDPETTLEDTIASPPINAERLLQLITDEYESLPRQLKRIASYMSQQSDRIMVDRISD
IARECEVHPSAIVRFSQRFGFSGFSEMQALFREAYTHKTTPVQNYQQRIRSMIANKSQKA
SGGDLARECVNATLSGIERLGLELDDVAFDKAVDLVVNADNIYVVGVRRSFAVADYLVYN
LQHTNKRIHLISGLGGSYREQMRSVRANDLVIAISFTPYGKETQHCLRIAQHHQAKTLII
TDSNLSPLAKRANAVLLVNEGSSFAFRSLSATLCLCQALFIAVAYRLELKVDEIHEQVGF
DD