Protein Info for GFF231 in Hydrogenophaga sp. GW460-11-11-14-LB1

Annotation: probable DNA repair exonuclease

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 262 PF00149: Metallophos" amino acids 3 to 190 (188 residues), 54.7 bits, see alignment E=1.8e-18 PF12850: Metallophos_2" amino acids 4 to 216 (213 residues), 37 bits, see alignment E=3.4e-13

Best Hits

KEGG orthology group: None (inferred from 67% identity to rfr:Rfer_2358)

Predicted SEED Role

"probable DNA repair exonuclease"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (262 amino acids)

>GFF231 probable DNA repair exonuclease (Hydrogenophaga sp. GW460-11-11-14-LB1)
LSTILQVSDPHFGTERAPVVRALVQLAQRLRPDLVVLSGDITQRARARQFEAARRFMDQL
GAPRLVIPGNHDIPLFNGWARLMRPYAGHRAAFGDELEPEFSSTGLMVLAVNTTRAHRHK
NGEVSVAQVARVAARLAEATPAQLRVVVVHQPIDVQRPQDEPDRLIGHAAAQDAWAAAGA
DLVMGGHIHLPYVMPLPGLARPLWAVQAGTAVSRRVRPGAPNSVNLVRWHAVERACAIEQ
WDFSATEQAFVQVRVTRLQPAR