Protein Info for GFF2309 in Sphingobium sp. HT1-2

Annotation: Di-tripeptide/cation symporter

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 509 transmembrane" amino acids 34 to 53 (20 residues), see Phobius details amino acids 59 to 80 (22 residues), see Phobius details amino acids 89 to 107 (19 residues), see Phobius details amino acids 120 to 146 (27 residues), see Phobius details amino acids 160 to 180 (21 residues), see Phobius details amino acids 186 to 206 (21 residues), see Phobius details amino acids 231 to 251 (21 residues), see Phobius details amino acids 257 to 275 (19 residues), see Phobius details amino acids 287 to 305 (19 residues), see Phobius details amino acids 337 to 356 (20 residues), see Phobius details amino acids 368 to 390 (23 residues), see Phobius details amino acids 397 to 419 (23 residues), see Phobius details amino acids 431 to 453 (23 residues), see Phobius details amino acids 473 to 492 (20 residues), see Phobius details TIGR00924: amino acid/peptide transporter (Peptide:H+ symporter)" amino acids 13 to 496 (484 residues), 390.1 bits, see alignment E=8.9e-121 PF07690: MFS_1" amino acids 33 to 449 (417 residues), 66.3 bits, see alignment E=2.4e-22 PF00854: PTR2" amino acids 88 to 457 (370 residues), 223.5 bits, see alignment E=4.5e-70

Best Hits

KEGG orthology group: K03305, proton-dependent oligopeptide transporter, POT family (inferred from 58% identity to sjp:SJA_C1-23260)

Predicted SEED Role

"Di-/tripeptide transporter"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (509 amino acids)

>GFF2309 Di-tripeptide/cation symporter (Sphingobium sp. HT1-2)
MATAITVPAEAGKTWLGHPRGLFLLFFAEMWERFSYYGMRAILIFYLTKHFLFGEDKAYI
LYGAYTSLVYITPVIGGYLADRFLGPRKAVLVGGVFIAIGHFLIAITEGPGGQDAFYLNG
FYLALASIIVGTGFLKANISVLVGELYARDDHRRDPAFSIFYMGINLGGASGPIVCGLLG
ELWGWSWGFGAAGVGMLLGLVMFVWLRPWLLGKGEPPAPEKLRAPAIGTISQEWTIYASA
ALGVAAIWMVIRYAELLGYTLLIFSALTVAYILWRSATVLTRVERDRMFAALFLIALNPL
FWGLFEQTGSSLNIFTDRNVDRVILGWDVPASLFQSVNSIYIILLAPLFAVLWTFLDKRR
LEPSSPAKFGIGLILCGAGFLVLVAGAAMAGQSLTPVIFVFLIYLLHTMAELCFSPVGLS
AMTRLSVSNMVGLVMGTWFLAMAAGNFIAGLIARATGSGEAGDVTQVLDVYSRIGWFSVV
VGGLVLLVSPYVKRMMHLDLIAAEKGKQA