Protein Info for GFF2307 in Hydrogenophaga sp. GW460-11-11-14-LB1

Annotation: Phosphate regulon transcriptional regulatory protein PhoB (SphR)

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 243 PF00072: Response_reg" amino acids 9 to 118 (110 residues), 101.2 bits, see alignment E=3.8e-33 PF00486: Trans_reg_C" amino acids 161 to 235 (75 residues), 75.8 bits, see alignment E=2.3e-25

Best Hits

Swiss-Prot: 46% identical to VIRG_AGRRH: Regulatory protein VirG (virG) from Agrobacterium rhizogenes

KEGG orthology group: None (inferred from 64% identity to vpe:Varpa_4087)

Predicted SEED Role

"Phosphate regulon transcriptional regulatory protein PhoB (SphR)" in subsystem High affinity phosphate transporter and control of PHO regulon or Phosphate metabolism

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (243 amino acids)

>GFF2307 Phosphate regulon transcriptional regulatory protein PhoB (SphR) (Hydrogenophaga sp. GW460-11-11-14-LB1)
MSTAHVPHILVIDDDADVRDLVVEYLGKNDMRVSAGGSGAEMFALFDQEAIDLVLLDLRL
PGEDGMHLARALRERATVPIVLLTGRSEEADRVMGLELGADDYVTKPFSPRELLARVRAV
LRRYQVQATLPERDNTRRAYRFSGWELNLRTRRLVSPAGGSVELSNGEFSLLNALCRAPQ
RVLSRDQLLSMSRLHEAEVYDRTIDVQIRRLRLKVESDPTNPRLILTERGAGYRLASEVE
TLF