Protein Info for GFF2296 in Pseudomonas sp. DMC3

Annotation: hypothetical protein

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 325 transmembrane" amino acids 232 to 249 (18 residues), see Phobius details amino acids 298 to 323 (26 residues), see Phobius details PF08659: KR" amino acids 7 to 167 (161 residues), 58 bits, see alignment E=1.9e-19 PF00106: adh_short" amino acids 7 to 192 (186 residues), 135.2 bits, see alignment E=3e-43 PF13561: adh_short_C2" amino acids 11 to 193 (183 residues), 85.8 bits, see alignment E=5.2e-28

Best Hits

KEGG orthology group: None (inferred from 67% identity to pmy:Pmen_2357)

Predicted SEED Role

"Short-chain dehydrogenase/reductase SDR"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (325 amino acids)

>GFF2296 hypothetical protein (Pseudomonas sp. DMC3)
MQEQPLVVISGASAGVGRAVAHRFAAGGYRIGLLARDPAGLAATQEELQAYGVQVETVSV
DVADALAVQEAAQQLEAALGPLAVWVNAAMVTVLAPIEQLSAAEIERVTQVTYLGTVHGT
LAALSLMRPRNQGVIIQVGSALAYRAIPLQAAYCGAKFAVRGFTDSLRCELLHERSHIRV
CMVQLPAINTPQFDWARNKLPKRPQPVPPIHDPDVAARAIFSVVKRPPRELWLGWSTIKA
IVGQSVMPGLLDRLMARSAWSGQQTNEPEDNEHPDNLFEAQPDRHQIRGRFIGRSKDAAL
ALTSTQVLAVSAVIAVLVGVVLLQL