Protein Info for GFF229 in Variovorax sp. SCN45

Annotation: ABC transporter, substrate-binding protein (cluster 5, nickel/peptides/opines)

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 550 604 signal peptide" amino acids 1 to 19 (19 residues), see Phobius details PF00496: SBP_bac_5" amino acids 98 to 510 (413 residues), 246.5 bits, see alignment E=2.5e-77

Best Hits

KEGG orthology group: K13893, microcin C transport system substrate-binding protein (inferred from 90% identity to vpe:Varpa_2842)

Predicted SEED Role

"ABC transporter, periplasmic substrate-binding protein"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (604 amino acids)

>GFF229 ABC transporter, substrate-binding protein (cluster 5, nickel/peptides/opines) (Variovorax sp. SCN45)
MRFLWAWSLMVCAVPAWAAHGYALWDDLKYGPDFKAFDYVDPAAPKGGELRLVSNLRVST
FDKYNPFTIKGSAPAYLDSLLFDTLLTGSMDETASGYGLLAEDVTVAPDRRSVTFRLRPE
ARFHNGMPVEAADVKHSYDTLIGPYTSPGYKTLLQEVDGADVIDARTIRFRFKTPNRELP
LIVGSLPIFSRAWGVENGKAKPFDQVVMDIPIGSGAYKIGPVRFGKDITYVRDPGYWARD
LPVNRGSHNFDRITVKIYKDNTARLEALKAGEFDMMSFYSAGDWARRVNGKRFNTGELVK
REFQHKKPAGFQSFVLNSRRDKLKDPRVREALGLALDYEWMNRQMFYGGYPRVTDLFGNT
DCEAKGLPSPEEKALLEPWRGKIPDASFGPMYTPPTTEGEGHSLRNNLRRARDLLKEAGW
EYRDGALRNAKGERMTLEYLDSKEGGVRTVSPWVRNLEKLGITLNFATVDFALYQERLDR
FDFDITTINFPGTNNPGQSLLEIFGSKAAKTESSGNYMGVSTPAIDALLKDIVDADTKAE
LMPACRALDRVIMHSHYLIPQWTLTSHRIVYDDWRLSFKSPMPPYAGGEDWVMGTWWAKQ
PPKQ