Protein Info for GFF2289 in Variovorax sp. SCN45

Annotation: Glutathione-regulated potassium-efflux system ancillary protein KefF

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 235 PF02525: Flavodoxin_2" amino acids 11 to 178 (168 residues), 140 bits, see alignment E=4.2e-45

Best Hits

KEGG orthology group: K11746, glutathione-regulated potassium-efflux system ancillary protein KefF (inferred from 85% identity to vpe:Varpa_5062)

Predicted SEED Role

"Glutathione-regulated potassium-efflux system ancillary protein KefF" in subsystem Glutathione-regulated potassium-efflux system and associated functions or Potassium homeostasis

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (235 amino acids)

>GFF2289 Glutathione-regulated potassium-efflux system ancillary protein KefF (Variovorax sp. SCN45)
MGNTAAGPGGIYVLAAHPHWRDSRVNRRMLAAARAVPGVDVNDLYGSYPDFSIDIEAEQA
RLSQASLVVLLHPIQWYSMPALQKLWLDDVLAYGWAYGPGGTALQGKDLWLVATTGSPEP
SYHPQSYHRYFFDAFLPPYEQTAALCGMRFLPPLIFYGARSAPEAEVAAHVQTFAQRLGS
YPDWPEIEELDTCIACPVPETDRPADSDDIGKVVSNAFHAAMTHGLAAASTSKAP