Protein Info for GFF2284 in Pseudomonas sp. DMC3

Annotation: Peroxiredoxin Bcp

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

• PF00578: AhpC-TSA
  • amino acids 5 to 133 (129 residues), 127.9 bits, E=2.1e-41
• PF08534: Redoxin
  • amino acids 7 to 140 (134 residues), 62.7 bits, E=3.4e-21

Best Hits

Swiss-Prot: 48% identical to BCP_COXBU: Putative peroxiredoxin bcp (bcp) from Coxiella burnetii (strain RSA 493 / Nine Mile phase I)

KEGG orthology group: K03564, peroxiredoxin Q/BCP [EC: 1.11.1.15] (inferred from 95% identity to pfl:PFL_1455)

MetaCyc: 41% identical to thiol peroxidase (Escherichia coli K-12 substr. MG1655)
1.11.1.15-RXN [EC: 1.11.1.24]

Predicted SEED Role

"Thiol peroxidase, Bcp-type (EC 1.11.1.15)" in subsystem Thioredoxin-disulfide reductase (EC 1.11.1.15)

KEGG Metabolic Maps

• Glutathione metabolism

Isozymes

Compare fitness of predicted isozymes for: 1.11.1.15

Use Curated BLAST to search for 1.11.1.15 or 1.11.1.24

Protein Sequence (157 amino acids)

>GFF2284 Peroxiredoxin Bcp (Pseudomonas sp. DMC3)
MAVAIDQPVADFTAPATSGQTVSLSELKGKQVVIYFYPKDSTPGCTTQGQGFRDQYAAFK
AANTEVFGISRDSLKSHENFKGKQEFPFELISDKDEAVCQLFDVIKLKKLYGKEYLGVDR
STFLIDKDGVLRQEWRGVKVPGHVDAVLAAAEALNKA