Protein Info for GFF2267 in Sphingobium sp. HT1-2

Annotation: Peptidase B (EC 3.4.11.23)

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 483 PF21337: Peptidase_M17_N_1" amino acids 37 to 139 (103 residues), 63.8 bits, see alignment E=1.6e-21 PF00883: Peptidase_M17" amino acids 168 to 470 (303 residues), 339 bits, see alignment E=2.9e-105

Best Hits

KEGG orthology group: K01255, leucyl aminopeptidase [EC: 3.4.11.1] (inferred from 76% identity to sch:Sphch_0239)

Predicted SEED Role

"Peptidase B (EC 3.4.11.23)" (EC 3.4.11.23)

KEGG Metabolic Maps

Isozymes

Compare fitness of predicted isozymes for: 3.4.11.1

Use Curated BLAST to search for 3.4.11.1 or 3.4.11.23

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (483 amino acids)

>GFF2267 Peptidase B (EC 3.4.11.23) (Sphingobium sp. HT1-2)
MTKNGPFPCGALSPTSLCMTEFADLLKADNGQPARSIQLIEAAELDAWFTTQPERVRALI
SAQKFHAKPNEYAIIPGEGQSDWSVVAGVVKRDALGSWCLARLAESLPEGSYRLAEGSTG
AAALGWLTAQYRFERYRKDEGAAGPRVLLTGDVARIEAIVQQAEAVALVRDLVNTPAADM
GPQDLEDAVRQLAQAHGGEVQVTRGDALEQGFPMIHAVGKAADKGFAPRLIEMSWGDPAA
PRIAVIGKGICFDSGGLDIKPSSGMRLMKKDMGGAAHAIALARLIIGARLPVRLHLLVPT
AENAISGNAFRPGDILRSRQGLTVEIGNTDAEGRLVLGDALTRAGEEKPELIVDFATLTG
AARVAVGPDLPALFTNDEALASDIAAAGTAVDDPTWRLPLWDGYYDMLKSDIADMNNAGE
GGFAGAVTAALFLQRFVPEGTAWIHLDTFAWRPAARPGRPKGGEALGLRAVFRLLQQRYD
GAR