Protein Info for GFF2224 in Salmonella enterica subsp. enterica serovar Typhimurium str. MS1868

Annotation: Putative hydrolase

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 244 PF05116: S6PP" amino acids 4 to 214 (211 residues), 70.1 bits, see alignment E=5.6e-23 TIGR01484: HAD hydrolase, family IIB" amino acids 5 to 208 (204 residues), 90.6 bits, see alignment E=1.6e-29 PF08282: Hydrolase_3" amino acids 6 to 95 (90 residues), 82.8 bits, see alignment E=8.9e-27 amino acids 114 to 235 (122 residues), 103.4 bits, see alignment E=4.4e-33

Best Hits

KEGG orthology group: K07024, (no description) (inferred from 99% identity to set:SEN3797)

Predicted SEED Role

"Putative hydrolase"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (244 amino acids)

>GFF2224 Putative hydrolase (Salmonella enterica subsp. enterica serovar Typhimurium str. MS1868)
MRYRLIAFDLDGTLLNRNKQILPESLTAIRQMQDMGCRIMLVTGRSHREAYAYYQTLALT
EPMICCNGSYIYQPAQQQILHPLPLTHLQTEKILARVYPLKPTIRADDKIIFQADELSSR
ENIWQISIVHRHIKQLQNIAEFIQHELHLSCTWSWHHQLDILQKGCSKGQSLARYAQQQH
IAMREVMAFGDNDNDAEMLRLAGLGVAMGNASARAKVYADSVIGRHNTPAIADFLATLSL
SQRE