Protein Info for GFF2216 in Variovorax sp. SCN45

Annotation: Uncharacterized protein Tbd_1903

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 373 signal peptide" amino acids 1 to 36 (36 residues), see Phobius details PF13432: TPR_16" amino acids 42 to 101 (60 residues), 29.7 bits, see alignment E=3.3e-10 amino acids 109 to 160 (52 residues), 28.2 bits, see alignment 9.5e-10 PF14559: TPR_19" amino acids 80 to 139 (60 residues), 32.1 bits, see alignment E=5.5e-11 PF13181: TPR_8" amino acids 106 to 135 (30 residues), 19.4 bits, see alignment (E = 4e-07) PF13414: TPR_11" amino acids 112 to 150 (39 residues), 32.5 bits, see alignment 2.4e-11 PF24125: Cds6_C" amino acids 266 to 369 (104 residues), 53.9 bits, see alignment E=9.2e-18

Best Hits

KEGG orthology group: None (inferred from 84% identity to vpe:Varpa_5146)

Predicted SEED Role

"TPR repeat precursor"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (373 amino acids)

>GFF2216 Uncharacterized protein Tbd_1903 (Variovorax sp. SCN45)
MPKSPRPRARFSFSPTVRALFLAAATCGVALPALSAVEHEEVDKLMQAGKLDEAMTKADA
FLKDKPRDPQMRFLKGVIQLDTGKRAEAIAAFTQLTQDAPELPEPFNNLAVIYASQNQFD
KARAALESAIRTNPSYATAQENLGDVYARLASQAYSKALQLDQNNTAVQPKLAVIRTLFT
PTPAGGKSSTLVASAAPVPAPTPAPAPAPAVKAAAPAPAPAPAAPPPAKVAAAPAPVAAA
PKAPEAAPAPAPAPAPAASTASNAEVESAVRAWASAWASQDMDRYLAAYGSDFTPGGGQS
RKNWEQDRRARIVGKSSISVNIENLVIKVDGDNATAKFRQIYRADNLNVSSRKTLDMQRS
GNQWHIRKESVGG