Protein Info for GFF2209 in Hydrogenophaga sp. GW460-11-11-14-LB1

Annotation: Uptake hydrogenase small subunit precursor (EC 1.12.99.6)

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

• PF01058: Oxidored_q6
  • amino acids 13 to 178 (166 residues), 94.9 bits, E=3.2e-31
• PF14720: NiFe_hyd_SSU_C
  • amino acids 200 to 275 (76 residues), 81.6 bits, E=4.5e-27

Best Hits

KEGG orthology group: K00534, ferredoxin hydrogenase small subunit [EC: 1.12.7.2] (inferred from 88% identity to mpt:Mpe_A2807)

Predicted SEED Role

"Uptake hydrogenase small subunit precursor (EC 1.12.99.6)" in subsystem Hydrogenases or Membrane-bound Ni, Fe-hydrogenase (EC 1.12.99.6)

MetaCyc Pathways

• hydrogen oxidation I (aerobic) (1/1 steps found)
• hydrogen production III (1/1 steps found)
• hydrogen production VIII (1/1 steps found)
• hydrogen production VI (1/2 steps found)
• superpathway of hydrogen production (1/2 steps found)
• superpathway of photosynthetic hydrogen production (3/6 steps found)
• superpathway of fermentation (Chlamydomonas reinhardtii) (4/9 steps found)
• L-glutamate degradation VII (to butanoate) (5/12 steps found)

KEGG Metabolic Maps

• Glyoxylate and dicarboxylate metabolism
• Methane metabolism
• Trinitrotoluene degradation

Isozymes

Compare fitness of predicted isozymes for: 1.12.99.6

Use Curated BLAST to search for 1.12.7.2 or 1.12.99.6

Protein Sequence (333 amino acids)

>GFF2209 Uptake hydrogenase small subunit precursor (EC 1.12.99.6) (Hydrogenophaga sp. GW460-11-11-14-LB1)
MALNVLWLQSGGCGGCSMSLLCADTTDFQGHLRDAGVNLLWHPSLSMESGDELLDLLDAV
LDGRTRLDALCVEGSLLRGPNGTGRFHMLAGTQLPMIEWVKRLSARAKHVLAVGSCAAWG
GITAGGDNPTDACGLQYEDDEAGGLLGAAFRSASGLPVINIAGCPTHPSWVIDTLMALAA
DSFGAGELDPLNRPRFYADQLVHHGCTRNEYYEFKASAEKPSDLGCMMEHMGCKGTQVHA
DCNTRLWNGEGSCTRGGYACIACTEPGFQEPGHPFHETPKLAGIPIGLPTDMPKAWFVAL
ASLSKSATPKRVKHNAVADHLVVTPAVRKTRLK